Protein Overview: CLN3

General Information:
Name(s) found:	CLN3 [HGNC (HUGO)]
Description(s) found: Found 60 descriptions. SHOW ALL	ceroid-lipofuscinosis, neuronal 3 [HGNC (HUGO)]
Organism:	Homo sapiens
Length:	438 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGCAGSRRR FSDSEGEETV PEPRLPLLDH QGAHWKNAVG FWLLGLCNNF SYVVMLSAAH  60
   61 DILSHKRTSG NQSHVDPGPT PIPHNSSSRF DCNSVSTAAV LLADILPTLV IKLLAPLGLH 120
  121 LLPYSPRVLV SGICAAGSFV LVAFSHSVGT SLCGVVFASI SSGLGEVTFL SLTAFYPRAV 180
  181 ISWWSSGTGG AGLLGALSYL GLTQAGLSPQ QTLLSMLGIP ALLLASYFLL LTSPEAQDPG 240
  241 GEEEAESAAR QPLIRTEAPE SKPGSSSSLS LRERWTVFKG LLWYIVPLVV VYFAEYFINQ 300
  301 GLFELLFFWN TSLSHAQQYR WYQMLYQAGV FASRSSLRCC RIRFTWALAL LQCLNLVFLL 360
  361 ADVWFGFLPS IYLVFLIILY EGLLGGAAYV NTFHNIALET SDEHREFAMA ATCISDTLGI 420
  421 SLSGLLALPL HDFLCQLS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..438]	FFAS03	1.83	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transporter activity	3.82096685159505	bayes_pls_golite062009
transmembrane transporter activity	3.34396155292818	bayes_pls_golite062009
substrate-specific transporter activity	3.32643461660963	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.2506965512085	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.05049771748124	bayes_pls_golite062009
ion transmembrane transporter activity	2.02370427376594	bayes_pls_golite062009
binding	1.9065830290222	bayes_pls_golite062009
cation transmembrane transporter activity	1.62538016506437	bayes_pls_golite062009
active transmembrane transporter activity	1.46819549608723	bayes_pls_golite062009
secondary active transmembrane transporter activity	0.869150152038001	bayes_pls_golite062009
polyol transmembrane transporter activity	0.339747214378126	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.339747214378126	bayes_pls_golite062009
symporter activity	0.327558013224678	bayes_pls_golite062009
solute:cation symporter activity	0.327558013224678	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	0.273403673499648	bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity	0.273403673499648	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.222664452597504	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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