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Protein Overview: IPI:IPI00037070....

General Information:
Name(s) found: IPI:IPI00037070.1|SWISS-PROT:P11142-2|REFSEQ_NP:NP_694881|ENSEMBL:ENSP00000278904 [hmr_yeast5_DM3-1_pombe.fasta]
IPI:IPI00037070.1|SWISS-PROT:P11142-2|TREMBL:Q53HF2|REFSEQ_NP:NP_694881|ENSEMBL:ENSP00000278904 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
Description(s) found:
Found 4 descriptions.
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  • Splice isoform 2 of P11142 Heat shock cognate 71 kDa protein [hmr_yeast5_DM3-1_pombe.fasta]
  • Tax_Id=9606 Splice Isoform 2 of Heat shock cognate 71 kDa protein [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
    • Organism: Homo sapiens
    Length: 497 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKGPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNQVA  60
   61 MNPTNTVFDA KRLIGRRFDD AVVQSDMKHW PFMVVNDAGR PKVQVEYKGE TKSFYPEEVS 120
  121 SMVLTKMKEI AEAYLGKTVT NAVVTVPAYF NDSQRQATKD AGTIAGLNVL RIINEPTAAA 180
  181 IAYGLDKKVG AERNVLIFDL GGGTFDVSIL TIEDGIFEVK STAGDTHLGG EDFDNRMVNH 240
  241 FIAEFKRKHK KDISENKRAV RRLRTACERA KRTLSSSTQA SIEIDSLYEG IDFYTSITRA 300
  301 RFEELNADLF RGTLDPVEKA LRDAKLDKSQ IHDIVLVGGS TRIPKIQKLL QDFFNGKELN 360
  361 KSINPDEAVA YGAAVQAAIL SGDKSENVQD LLLLDVTPLS LGIETAGGVM TVLIKRNTTI 420
  421 PTKQTQTFTT YSDNQPGVLI QVYEGERAMT KDNNLLGKFE LTGIPPAPRG GMPGGFPGGG 480
  481 APPSGGASSG PTIEEVD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CENPA No Comments Foltz DR, et al (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..497] PSI-BLAST 1000.0 crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • unfolded protein binding
    		•  2.80511977200055 bayes_pls_golite062009
  • binding
    		•  1.54134537534661 bayes_pls_golite062009
  • protein binding
    		•  1.16405332128302 bayes_pls_golite062009
  • kinase activity
    		•  0.641356183582417 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.546260119151063 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.296022504929148 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.28741807440215 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0051518674395068 bayes_pls_golite062009
  • chaperone binding
    		•  0.00111313452804307 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle