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Protein Overview: INSL3

General Information:
Name(s) found: INSL3 [HGNC (HUGO)]
Description(s) found:
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  • gi|76826942|gb|AAI06722.1| Insulin-like 3 (Leydig cell) [Homo sapiens] [NCBI NR]
  • gi|632799|gb|AAB31371.1| Ley I-L [Homo sapiens] [NCBI NR]
  • pir||B53024 Leydig insulin-like protein precursor - human [NCBI NR]
  • gi|48735292|gb|AAH71706.1| Insulin-like 3 (Leydig cell) [Homo sapiens] [NCBI NR]
  • gi|194380434|dbj|BAG63984.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|1708497|sp|P51460.1|INSL3_HUMAN RecName: Full=Insulin-like 3; AltName: Full=Leydig insulin-like peptide; Short=Ley-I-L; AltName: Full=Relaxin-like factor; Contains: RecName: Full=Insulin-like 3 B chain; Contains: RecName: Full=Insulin-like 3 A chain; F [NCBI NR]
  • insulin-like 3 (Leydig cell) [HGNC (HUGO)]
  • Insulin-like 3 OS=Homo sapiens GN=INSL3 PE=1 SV=1 [Swiss-Prot]
  • (P51460) Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Swiss-Prot]
  • Leydig insulin-like peptide precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • Insulin-like 3, precursor [Homo sapiens]gi|539629|pir||B53024 Leydig insulin-like protein precursor - humangi|632799|gb|AAB31371.1| Ley I-L [Homo sapiens]gi|1708497|sp|P51460|INL3_HUMAN Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) ( [nrdb_11152004_Chlamydomonas]
  • Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Contains: Insulin-like 3 B chain; Insulin-like 3 A chain] [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Insulin-like 3 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • Ley I-L [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Insulin-like 3 (Leydig cell) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 INSULIN-LIKE 3 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=INSL3 Insulin-like 3 [human-ipi-250309-contam.fasta]
  • IPI:IPI00018695.1|SWISS-PROT:P51460|ENSEMBL:ENSP00000321724|REFSEQ:NP_005534|H-INV:HIT000216429|VEGA:OTTHUMP00000076870 Tax_Id=9606 Gene_Symbol=INSL3;JAK3 Insulin-like 3 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Gene_Symbol=INSL3;JAK3 Insulin-like 3 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=INSL3;JAK3 Insulin-like 3 [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • P51460;B4DZ72;Q3KPI5;Q3KPI6;Q9UEA2;Q9UPH6; RecName: Full=Insulin-like 3; AltName: Full=Leydig insulin-like peptide; AltName: Full=Relaxin-like factor; Contains: RecName: Full=Insulin-like 3 B chain; Contains: RecName: Full=Insulin-like 3 A chain; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Insulin-like 3 OS=Homo sapiens GN=INSL3 [011711_HMR.fasta]
  • Insulin-like 3 OS=Homo sapiens GN=INSL3 PE=1 SV=2 VAR_013234 [swiss.HUMAN.20141123.contam.amyloid.poly.fasta]
    • Organism: Homo sapiens
    Length: 131 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPRLPAWAL VLLGPALVFA LGPAPTPEMR EKLCGHHFVR ALVRVCGGPR WSTEARRPAA  60
   61 GGDRELLQWL ERRHLLHGLV ADSNLTLGPG LQPLPQTSHH HRHHRAAATN PARYCCLSGC 120
  121 TQQDLLTLCP Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] FFAS03 1.85 Insulin-like growth factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  3.80740241653284 bayes_pls_golite062009
  • growth factor activity
    		•  2.35540962487153 bayes_pls_golite062009
  • insulin receptor binding
    		•  2.07370009250118 bayes_pls_golite062009
  • binding
    		•  2.01173427813744 bayes_pls_golite062009
  • protein binding
    		•  1.77449935345508 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  1.43236402003799 bayes_pls_golite062009
  • hormone activity
    		•  1.12793487496998 bayes_pls_golite062009
  • protein complex binding
    		•  0.356483073070673 bayes_pls_golite062009
  • growth factor binding
    		•  0.0768650951090168 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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