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View Structure Prediction Details

Protein: INSL3
Organism: Homo sapiens
Length: 131 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INSL3.

Description E-value Query
Range		 Subject
Range
gi|119605040, gi... - gi|76827690|gb|AAI06723.1| Insulin-like 3 (Leydig cell) [Homo sapiens], gi|38327535|ref|NP_005534.2|...
 164.0 [0..1] [131..1]
INSL3_PANTR - Insulin-like 3 OS=Pan troglodytes GN=INSL3 PE=3 SV=1
 163.0 [0..1] [131..1]
INSL3_PIG - Insulin-like 3 OS=Sus scrofa GN=INSL3 PE=2 SV=1
gi|539728 - pir||A53024 Leydig insulin-like protein precursor - pig
 162.0 [0..1] [131..1]
gi|38607270 - gi|38607270|gb|AAR25542.1| relaxin-like peptide hormone INSL3 [Capreolus capreolus]
 160.0 [0..1] [131..1]
gi|7689351 - gi|7689351|gb|AAF67742.1| relaxin-like protein [Cervus dama]
 160.0 [0..1] [131..1]
gi|67078442, gi|... - gi|94429011|gb|ABF18930.1| insulin-like protein 3 [Ovis aries], gi|67078442|ref|NP_001019909.1| insu...
 160.0 [0..1] [131..1]
INSL3_BOVIN - Insulin-like 3 OS=Bos taurus GN=INSL3 PE=1 SV=1
 156.0 [0..1] [131..1]

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Predicted Domain #1
Region A:
Residues: [1-131] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPRLPAWAL VLLGPALVFA LGPAPTPEMR EKLCGHHFVR ALVRVCGGPR WSTEARRPAA  60
   61 GGDRELLQWL ERRHLLHGLV ADSNLTLGPG LQPLPQTSHH HRHHRAAATN PARYCCLSGC 120
  121 TQQDLLTLCP Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.85
Match: 3lriA
Description: Insulin-like growth factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 3.80740241653284 bayes_pls_golite062009
growth factor activity 2.35540962487153 bayes_pls_golite062009
insulin receptor binding 2.07370009250118 bayes_pls_golite062009
binding 2.01173427813744 bayes_pls_golite062009
protein binding 1.77449935345508 bayes_pls_golite062009
insulin-like growth factor receptor binding 1.43236402003799 bayes_pls_golite062009
hormone activity 1.12793487496998 bayes_pls_golite062009
protein complex binding 0.356483073070673 bayes_pls_golite062009
growth factor binding 0.0768650951090168 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle