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Protein Overview: PDCD2

General Information:
Name(s) found: PDCD2 [HGNC (HUGO)]
Description(s) found:
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  • gi|3790133|emb|CAA20285.1| programmed cell death 2 [Homo sapiens] [NCBI NR]
  • gi|28202261|sp|Q16342.2|PDCD2_HUMAN RecName: Full=Programmed cell death protein 2; AltName: Full=Zinc finger protein Rp-8; AltName: Full=Zinc finger MYND domain-containing protein 7 [NCBI NR]
  • gi|21735592|ref|NP_002589.2| programmed cell death 2 isoform 1 [Homo sapiens] [NCBI NR]
  • gi|14249983|gb|AAH08378.1| Programmed cell death 2 [Homo sapiens] [NCBI NR]
  • gi|119567802|gb|EAW47417.1| programmed cell death 2, isoform CRA_e [Homo sapiens] [NCBI NR]
  • programmed cell death 2 [HGNC (HUGO)]
  • Programmed cell death protein 2 OS=Homo sapiens GN=PDCD2 PE=1 SV=2 [Swiss-Prot]
  • (Q16342) Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain containing protein 7) [Swiss-Prot]
  • Programmed cell death protein 2 [hmr_yeast5_DM3-1_pombe.fasta]
  • programmed cell death 2 isoform 1; zinc finger protein Rp-8; programmed cell death 2/Rp8 homolog [HMR_022704.fasta]
  • programmed cell death 2 isoform 1 [Homo sapiens]gi|14249983|gb|AAH08378.1| Programmed cell death 2, isoform 1 [Homo sapiens]gi|3790133|emb|CAA20285.1| dJ191N21.1.1 (Programmed cell death 2, variant 1) [Homo sapiens]gi|28202261|sp|Q16342|PCD2_HUMAN Prog [nrdb_11152004_Chlamydomonas]
  • Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain containing protein 7) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Programmed cell death protein 2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_002598) programmed cell death 2, isoform 1; zinc finger protein Rp-8; programmed cell death 2/Rp8 homolog [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • programmed cell death 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • programmed cell death 2 isoform 1; zinc finger protein Rp-8; programmed cell death 2/Rp8 homolog [Homo sapiens] [HumanGallus06162005.fasta]
  • Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • programmed cell death 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • programmed cell death 2, isoform CRA_e [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Programmed cell death 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 PROGRAMMED CELL DEATH PROTEIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PDCD2 Programmed cell death protein 2 [human-ipi-250309-contam.fasta]
  • IPI:IPI00001427.6|SWISS-PROT:Q16342|ENSEMBL:ENSP00000167218|REFSEQ:NP_002589|H-INV:HIT000033754|VEGA:OTTHUMP00000017701 Tax_Id=9606 Gene_Symbol=PDCD2 Programmed cell death protein 2 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PDCD2 Programmed cell death protein 2 ENSG00000071994 IPI00001427 IPI00376691 IPI00749327 IPI00432847 [drosphohumanreversed.fasta]
  • programmed cell death protein 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q16342;Q9UH12; RecName: Full=Programmed cell death protein 2; AltName: Full=Zinc finger protein Rp-8; AltName: Full=Zinc finger MYND domain-containing protein 7; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Programmed cell death protein 2 OS=Homo sapiens GN=PDCD2 [011711_HMR.fasta]
  • GeneSymbol=PDCD2 Synonyms=MGC12347|RP8|ZMYND7 programmed cell death protein 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00001427.6|SWISS-PROT:Q16342|ENSEMBL:ENSP00000439467|REFSEQ:NP_002589|H-INV:HIT000033754|VEGA:OTTHUMP00000017701 Tax_Id=9606 Gene_Symbol=PDCD2 Programmed cell death protein 2 [ipi.HUMAN.20110912.fasta]
  • Programmed cell death protein 2 GN=PDCD2 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 344 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAGARPVE LGFAESAPAW RLRSEQFPSK VGGRPAWLGA AGLPGPQALA CELCGRPLSF  60
   61 LLQVYAPLPG RPDAFHRCIF LFCCREQPCC AGLRVFRNQL PRKNDFYSYE PPSENPPPET 120
  121 GESVCLQLKS GAHLCRVCGC LGPKTCSRCH KAYYCSKEHQ TLDWRLGHKQ ACAQPDHLDH 180
  181 IIPDHNFLFP EFEIVIETED EIMPEVVEKE DYSEIIGSMG EALEEELDSM AKHESREDKI 240
  241 FQKFKTQIAL EPEQILRYGR GIAPIWISGE NIPQEKDIPD CPCGAKRILE FQVMPQLLNY 300
  301 LKADRLGKSI DWGILAVFTC AESCSLGTGY TEEFVWKQDV TDTP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] FFAS03 1.07 Structure of Hypothetical Protein Ywqg from Bacillus subtilis
    2 View Details [112..181] PSI-BLAST 9.0 No description for 2dj8A was found.
    3 View Details [182..344] Pfam 119.244125 No description for PF04194.4 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.84945259695526 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.545865021201494 bayes_pls_golite062009
  • protein binding
    		•  0.425029114798138 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.411475115290625 bayes_pls_golite062009
  • DNA binding
    		•  0.354211088524398 bayes_pls_golite062009
  • transcription activator activity
    		•  0.24422052145333 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle