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Protein Overview: SULT1E1

General Information:
Name(s) found: SULT1E1 [HGNC (HUGO)]
Description(s) found:
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  • gi|998888|gb|AAB34601.1| estrogen sulfotransferase; hEST-1 [Homo sapiens] [NCBI NR]
  • pir||JC2229 estrogen sulfotransferase (EC 2.8.2.-) - human [NCBI NR]
  • gi|4885617|ref|NP_005411.1| sulfotransferase, estrogen-preferring [Homo sapiens] [NCBI NR]
  • gi|488283|gb|AAA82125.1| estrogen sulfotransferase [NCBI NR]
  • gi|47115179|emb|CAG28549.1| SULT1E1 [Homo sapiens] [NCBI NR]
  • gi|37675285|gb|AAQ97179.1| sulfotransferase, estrogen-preferring [Homo sapiens] [NCBI NR]
  • gi|34811080|pdb|1G3M|B Chain B, Crystal Structure Of Human Estrogen Sulfotransferase In Complex With In-Active Cofactor Pap And 3,5,3',5'- Tetrachloro-Biphenyl-4,4'-Diol [NCBI NR]
  • gi|34811079|pdb|1G3M|A Chain A, Crystal Structure Of Human Estrogen Sulfotransferase In Complex With In-Active Cofactor Pap And 3,5,3',5'- Tetrachloro-Biphenyl-4,4'-Diol [NCBI NR]
  • gi|189053343|dbj|BAG35169.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|1848073|emb|CAA72079.1| estrogen sulfotransferase [Homo sapiens] [NCBI NR]
  • gi|1711604|sp|P49888.1|ST1E1_HUMAN RecName: Full=Estrogen sulfotransferase; AltName: Full=Sulfotransferase, estrogen-preferring; AltName: Full=EST-1 [NCBI NR]
  • gi|119626002|gb|EAX05597.1| sulfotransferase family 1E, estrogen-preferring, member 1 [Homo sapiens] [NCBI NR]
  • gi|1079513|gb|AAC50286.1| estrogen sulfotransferase [NCBI NR]
  • sulfotransferase family 1E, estrogen-preferring, member 1 [HGNC (HUGO)]
  • (P49888) Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen-preferring) (EST-1) [Swiss-Prot]
  • Estrogen sulfotransferase OS=Homo sapiens GN=SULT1E1 PE=1 SV=1 [Swiss-Prot]
  • Estrogen sulfotransferase [hmr_yeast5_DM3-1_pombe.fasta]
  • sulfotransferase, estrogen-preferring; estrogen sulfotransferase; estrone sulfotransferase [HMR_022704.fasta]
  • sulfotransferase, estrogen-preferring [Homo sapiens]gi|4885617|ref|NP_005411.1| sulfotransferase, estrogen-preferring [Homo sapiens]gi|34811080|pdb|1G3M|B Chain B, Crystal Structure Of Human Estrogen Sulfotransferase In Complex With In-Active Cofactor P [nrdb_11152004_Chlamydomonas]
  • Estrogen sulfotransferase (Sulfotransferase, estrogen-preferring) (EST-1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Estrogen sulfotransferase [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_005420) sulfotransferase, estrogen-preferring [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • sulfotransferase, estrogen-preferring [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • sulfotransferase, estrogen-preferring; estrogen sulfotransferase; estrone sulfotransferase [Homo sapiens] [HumanGallus06162005.fasta]
  • Chain B, Crystal Structure Of Human Estrogen Sulfotransferase In Complex With In-Active Cofactor Pap And 3,5,3',5'- Tetrachloro-Biphenyl-4,4'-Diol [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain A, Crystal Structure Of Human Estrogen Sulfotransferase In Complex With In-Active Cofactor Pap And 3,5,3',5'- Tetrachloro-Biphenyl-4,4'-Diol [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • estrogen sulfotransferase; hEST-1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • sulfotransferase family 1E, estrogen-preferring, member 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • SULT1E1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • estrogen sulfotransferase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • estrogen sulfotransferase [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 ESTROGEN SULFOTRANSFERASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SULT1E1 Estrogen sulfotransferase [human-ipi-250309-contam.fasta]
  • IPI:IPI00028623.1|SWISS-PROT:P49888|TREMBL:Q53X91|ENSEMBL:ENSP00000226444|REFSEQ:NP_005411|H-INV:HIT000217829|VEGA:OTTHUMP00000159769 Tax_Id=9606 Gene_Symbol=SULT1E1 Estrogen sulfotransferase [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=SULT1E1 Estrogen sulfotransferase ENSG00000109193 IPI00028623 [drosphohumanreversed.fasta]
  • P49888;Q8N6X5; RecName: Full=Estrogen sulfotransferase; AltName: Full=Sulfotransferase, estrogen-preferring; AltName: Full=EST-1; AltName: Full=Sulfotransferase 1E1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Estrogen sulfotransferase OS=Homo sapiens GN=SULT1E1 [011711_HMR.fasta]
  • GeneSymbol=SULT1E1 Synonyms=EST|EST-1|MGC34459|STE estrogen sulfotransferase [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Estrogen sulfotransferase GN=SULT1E1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Sulfotransferase (Fragment) OS=Homo sapiens GN=SULT1E1 PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 294 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSELDYYEK FEEVHGILMY KDFVKYWDNV EAFQARPDDL VIATYPKSGT TWVSEIVYMI  60
   61 YKEGDVEKCK EDVIFNRIPF LECRKENLMN GVKQLDEMNS PRIVKTHLPP ELLPASFWEK 120
  121 DCKIIYLCRN AKDVAVSFYY FFLMVAGHPN PGSFPEFVEK FMQGQVPYGS WYKHVKSWWE 180
  181 KGKSPRVLFL FYEDLKEDIR KEVIKLIHFL ERKPSEELVD RIIHHTSFQE MKNNPSTNYT 240
  241 TLPDEIMNQK LSPFMRKGIT GDWKNHFTVA LNEKFDKHYE QQMKESTLKF RTEI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. SULT1E1 gi|112491310 gi|219109210, gi...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 72.69897 Estrogen sulfotransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.01755875920323 bayes_pls_golite062009
  • motor activity
    		•  1.56647300556411 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.48896543101005 bayes_pls_golite062009
  • nucleotide binding
    		•  0.294629388587597 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.258527744324945 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.219555040684154 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.218726793699558 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.21867107119713 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.198256709027213 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.197994873032963 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.145265867076169 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.065286528593603 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.0518105987344697 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle