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Protein Overview: PROK1

General Information:
Name(s) found: PROK1 [HGNC (HUGO)]
Description(s) found:
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  • gi|55664325|emb|CAH71489.1| prokineticin 1 [Homo sapiens] [NCBI NR]
  • gi|55664238|emb|CAH74102.1| prokineticin 1 [Homo sapiens] [NCBI NR]
  • gi|37182488|gb|AAQ89046.1| EG-VEGF [Homo sapiens] [NCBI NR]
  • gi|17380189|sp|P58294.1|PROK1_HUMAN RecName: Full=Prokineticin-1; AltName: Full=Endocrine-gland-derived vascular endothelial growth factor; Short=EG-VEGF; AltName: Full=Mambakine; Flags: Precursor [NCBI NR]
  • gi|17223630|gb|AAK33111.1| black mamba toxin-related protein [Homo sapiens] [NCBI NR]
  • gi|14165282|ref|NP_115790.1| prokineticin 1 [Homo sapiens] [NCBI NR]
  • gi|13936736|gb|AAK49918.1| prokineticin 1 precursor [Homo sapiens] [NCBI NR]
  • gi|119576854|gb|EAW56450.1| prokineticin 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119576853|gb|EAW56449.1| prokineticin 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • prokineticin 1 [HGNC (HUGO)]
  • Prokineticin-1 OS=Homo sapiens GN=PROK1 PE=1 SV=1 [Swiss-Prot]
  • (P58294) Prokineticin 1 precursor (Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine) (UNQ600/PRO1186) [Swiss-Prot]
  • Prokineticin 1 precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • prokineticin 1; prokineticin 1 precursor; black mamba toxin-related protein; mambakine [HMR_022704.fasta]
  • EG-VEGF [Homo sapiens]gi|14165282|ref|NP_115790.1| prokineticin 1 [Homo sapiens]gi|55664325|emb|CAH71489.1| Prokineticin 1 [Homo sapiens]gi|55664238|emb|CAH74102.1| Prokineticin 1 [Homo sapiens]gi|17223630|gb|AAK33111.1| black mamba toxin-related prot [nrdb_11152004_Chlamydomonas]
  • Prokineticin 1 precursor (Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Prokineticin-1 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_032414) prokineticin 1; prokineticin 1 precursor; black mamba toxin-related protein; mambakine [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • prokineticin 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Prokineticin 1 precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • prokineticin 1; prokineticin 1 precursor; black mamba toxin-related protein; mambakine [Homo sapiens] [HumanGallus06162005.fasta]
  • Prokineticin-1 precursor (Endocrine-gland-derived vascular endothelial growth factor) (EG-VEGF) (Mambakine) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • prokineticin 1, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • EG-VEGF [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • black mamba toxin-related protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • prokineticin 1 precursor [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 PROKINETICIN 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Prokineticin-1; AltName: Full=Endocrine-gland-derived vascular endothelial growth factor; Short=EG-VEGF; AltName: Full=Mambakine; Flags: Precursor [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PROK1 Prokineticin-1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00033482.3|SWISS-PROT:P58294|ENSEMBL:ENSP00000271331|REFSEQ:NP_115790|H-INV:HIT000252727|VEGA:OTTHUMP00000013289 Tax_Id=9606 Gene_Symbol=PROK1 Prokineticin-1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PROK1 Prokineticin-1 precursor ENSG00000143125 IPI00033482 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PROK1 Prokineticin-1 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • prokineticin-1 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P58294;Q5VWD4;Q8TC69; RecName: Full=Prokineticin-1; AltName: Full=Endocrine-gland-derived vascular endothelial growth factor; AltName: Full=Mambakine; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Prokineticin-1 OS=Homo sapiens GN=PROK1 [011711_HMR.fasta]
  • GeneSymbol=PROK1 Synonyms=EGVEGF|PK1|PRK1 prokineticin-1 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Prokineticin-1 GN=PROK1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Prokineticin 1, isoform CRA_a OS=Homo sapiens GN=PROK1 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 105 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGATRVSIM LLLVTVSDCA VITGACERDV QCGAGTCCAI SLWLRGLRMC TPLGREGEEC  60
   61 HPGSHKVPFF RKRKHHTCPC LPNLLCSRFP DGRYRCSMDL KNINF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 27.30103 MAMBA INTESTINAL TOXIN 1, NMR, 39 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  2.74936845623837 bayes_pls_golite062009
  • protein binding
    		•  1.72927214733574 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  1.47532551478533 bayes_pls_golite062009
  • binding
    		•  1.31058855384814 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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