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View Structure Prediction Details

Protein: PROK1
Organism: Homo sapiens
Length: 105 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PROK1.

Description E-value Query
Range		 Subject
Range
gi|19263965 - gi|19263965|gb|AAH25399.1| Prokineticin 1 [Homo sapiens]
gi|123981334, gi... - gi|123996175|gb|ABM85689.1| prokineticin 1 [synthetic construct], gi|123981334|gb|ABM82496.1| prokin...
 4.0E-41 [1..105] [1..105]
PROK1_RAT - Prokineticin-1 OS=Rattus norvegicus GN=Prok1 PE=3 SV=1
 1.0E-40 [1..105] [1..105]
gi|109013433 - gi|109013433|ref|XP_001101188.1| PREDICTED: similar to prokineticin 1 [Macaca mulatta]
 2.0E-40 [1..105] [1..105]
PROK1_MOUSE - Prokineticin-1 OS=Mus musculus GN=Prok1 PE=1 SV=1
 2.0E-39 [1..105] [1..105]
gi|73959906 - gi|73959906|ref|XP_547234.2| PREDICTED: similar to prokineticin 1 [Canis familiaris]
 7.0E-37 [1..104] [1..104]
BM8X_BOMMX - Prokineticin Bv8-like peptide 2 OS=Bombina maxima PE=1 SV=1
 8.0E-34 [1..97] [1..96]
BV8_BOMVA - Prokineticin Bv8 OS=Bombina variegata PE=1 SV=1
 9.0E-33 [1..97] [1..96]
BO8_BOMOR - Prokineticin Bo8 OS=Bombina orientalis PE=1 SV=1
 1.0E-32 [1..97] [1..96]
gi|50760515 - gi|50760515|ref|XP_425816.1| PREDICTED: similar to prokineticin 1 [Gallus gallus]
 2.0E-32 [15..105] [15..105]

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Predicted Domain #1
Region A:
Residues: [1-105] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGATRVSIM LLLVTVSDCA VITGACERDV QCGAGTCCAI SLWLRGLRMC TPLGREGEEC  60
   61 HPGSHKVPFF RKRKHHTCPC LPNLLCSRFP DGRYRCSMDL KNINF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.30103
Match: 1imtA
Description: MAMBA INTESTINAL TOXIN 1, NMR, 39 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor binding 2.74936845623837 bayes_pls_golite062009
protein binding 1.72927214733574 bayes_pls_golite062009
G-protein-coupled receptor binding 1.47532551478533 bayes_pls_golite062009
binding 1.31058855384814 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle