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Protein Overview: SKP2

General Information:
Name(s) found: SKP2 [HGNC (HUGO)]
Description(s) found:
Found 33 descriptions.
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  • S-phase kinase-associated protein 2 (p45) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRKHLQEIP DLSSNVATSF TWGWDSSKTS ELLSGMGVSA LEKEEPDSEN IPQELLSNLG  60
   61 HPESPPRKRL KSKGSDKDFV IVRRPKLNRE NFPGVSWDSL PDELLLGIFS CLCLPELLKV 120
  121 SGVCKRWYRL ASDESLWQTL DLTGKNLHPD VTGRLLSQGV IAFRCPRSFM DQPLAEHFSP 180
  181 FRVQHMDLSN SVIEVSTLHG ILSQCSKLQN LSLEGLRLSD PIVNTLAKNS NLVRLNLSGC 240
  241 SGFSEFALQT LLSSCSRLDE LNLSWCFDFT EKHVQVAVAH VSETITQLNL SGYRKNLQKS 300
  301 DLSTLVRRCP NLVHLDLSDS VMLKNDCFQE FFQLNYLQHL SLSRCYDIIP ETLLELGEIP 360
  361 TLKTLQVFGI VPDGTLQLLK EALPHLQINC SHFTTIARPT IGNKKNQEIW GIKCRLTLQK 420
  421 PSCL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..333] PSI-BLAST 14.0 No description for 2omxA was found.
    2 View Details [334..424] PSI-BLAST 22.09691 Skp2; Cyclin A/CDK2-associated p19, Skp2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.69661396118522 bayes_pls_golite062009
  • binding
    		•  1.23313855731605 bayes_pls_golite062009
  • receptor activity
    		•  0.823142813332745 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.710443686489925 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.569410390698942 bayes_pls_golite062009
  • signal transducer activity
    		•  0.405945668463821 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.405945668463821 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0574120480524489 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle