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Protein Overview: GGA1

General Information:
Name(s) found: GGA1 [HGNC (HUGO)]
Description(s) found:
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  • gi|9558729|ref|NP_037497.1| golgi associated, gamma adaptin ear containing, ARF binding protein 1 isoform 1 [Homo sapiens] [NCBI NR]
  • gi|7229484|gb|AAF42847.1|AF218584_1 GGA1 [Homo sapiens] [NCBI NR]
  • gi|7021539|gb|AAF35393.1|AF233521_1 gamma-adaptin related protein, GGA1 [Homo sapiens] [NCBI NR]
  • gi|6179912|gb|AAF05707.1|AF190862_1 ADP-ribosylation factor binding protein GGA1 [Homo sapiens] [NCBI NR]
  • gi|56417756|emb|CAI20369.1| golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Homo sapiens] [NCBI NR]
  • gi|56202857|emb|CAI20951.1| golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Homo sapiens] [NCBI NR]
  • gi|22761225|dbj|BAC11501.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|158254528|dbj|BAF83237.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|14548066|sp|Q9UJY5.1|GGA1_HUMAN RecName: Full=ADP-ribosylation factor-binding protein GGA1; AltName: Full=Golgi-localized, gamma ear-containing, ARF-binding protein 1; AltName: Full=Gamma-adaptin-related protein 1 [NCBI NR]
  • gi|119580573|gb|EAW60169.1| golgi associated, gamma adaptin ear containing, ARF binding protein 1, isoform CRA_b [Homo sapiens] [NCBI NR]
  • golgi-associated, gamma adaptin ear containing, ARF binding protein 1 [HGNC (HUGO)]
  • ADP-ribosylation factor-binding protein GGA1 OS=Homo sapiens GN=GGA1 PE=1 SV=1 [Swiss-Prot]
  • Splice isoform 1 of Q9UJY5 [hmr_yeast5_DM3-1_pombe.fasta]
  • ADP-ribosylation factor binding protein 1; gamma-adaptin related protein 1 [HMR_022704.fasta]
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1 isoform 1; gamma-adaptin related protein 1; ADP-ribosylation factor binding protein 1 [071204_hmrz_cont.fasta]
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1 isoform 1 [Homo sapiens]gi|6179912|gb|AAF05707.1| ADP-ribosylation factor binding protein GGA1 [Homo sapiens]gi|7021539|gb|AAF35393.1| gamma-adaptin related protein, GGA1 [Homo sapien [nrdb_11152004_Chlamydomonas]
  • ADP-ribosylation factor binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin related protein 1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of ADP-ribosylation factor-binding protein GGA1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_013365) ADP-ribosylation factor binding protein 1; gamma-adaptin related protein 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1 isoform 1; gamma-adaptin related protein 1; ADP-ribosylation factor binding protein 1 [Homo sapiens] [HumanGallus06162005.fasta]
  • ADP-ribosylation factor binding protein 1; gamma-adaptin related protein 1 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ADP-ribosylation factor binding protein GGA1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • GGA1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • gamma-adaptin related protein, GGA1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of ADP-ribosylation factor-binding protein GGA1 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=GGA1 Isoform 1 of ADP-ribosylation factor-binding protein GGA1 [human-ipi-250309-contam.fasta]
  • OTTHUMP00000028975 [Homo sapiens] [nr-271106-contam.fasta]
  • IPI:IPI00744361.1|SWISS-PROT:Q9UJY5-1|TREMBL:A8K3D3|ENSEMBL:ENSP00000341344|REFSEQ:NP_037497|H-INV:HIT000082291|VEGA:OTTHUMP00000028975 Tax_Id=9606 Gene_Symbol=GGA1 Isoform 1 of ADP-ribosylation factor-binding protein GGA1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • ADP-ribosylation factor-binding protein GGA1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9UJY5;A8K3D3;Q5TG07;Q9BW94;Q9UG00;Q9UGW0;Q9UGW1; RecName: Full=ADP-ribosylation factor-binding protein GGA1; AltName: Full=Golgi-localized, gamma ear-containing, ARF-binding protein 1; AltName: Full=Gamma-adaptin-related protein 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of ADP-ribosylation factor-binding protein GGA1 OS=Homo sapiens GN=GGA1 [011711_HMR.fasta]
  • IPI:IPI00744361.1|SWISS-PROT:Q9UJY5-1|ENSEMBL:ENSP00000341344|REFSEQ:NP_037497|H-INV:HIT000082291|VEGA:OTTHUMP00000028975 Tax_Id=9606 Gene_Symbol=GGA1 Isoform 1 of ADP-ribosylation factor-binding protein GGA1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=GGA1 Synonyms=- ADP-ribosylation factor-binding protein GGA1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • ADP-ribosylation factor-binding protein GGA1 GN=GGA1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 639 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPAMEPETL EARINRATNP LNKELDWASI NGFCEQLNED FEGPPLATRL LAHKIQSPQE  60
   61 WEAIQALTVL ETCMKSCGKR FHDEVGKFRF LNELIKVVSP KYLGSRTSEK VKNKILELLY 120
  121 SWTVGLPEEV KIAEAYQMLK KQGIVKSDPK LPDDTTFPLP PPRPKNVIFE DEEKSKMLAR 180
  181 LLKSSHPEDL RAANKLIKEM VQEDQKRMEK ISKRVNAIEE VNNNVKLLTE MVMSHSQGGA 240
  241 AAGSSEDLMK ELYQRCERMR PTLFRLASDT EDNDEALAEI LQANDNLTQV INLYKQLVRG 300
  301 EEVNGDATAG SIPGSTSALL DLSGLDLPPA GTTYPAMPTR PGEQASPEQP SASVSLLDDE 360
  361 LMSLGLSDPT PPSGPSLDGT GWNSFQSSDA TEPPAPALAQ APSMESRPPA QTSLPASSGL 420
  421 DDLDLLGKTL LQQSLPPESQ QVRWEKQQPT PRLTLRDLQN KSSSCSSPSS SATSLLHTVS 480
  481 PEPPRPPQQP VPTELSLASI TVPLESIKPS NILPVTVYDQ HGFRILFHFA RDPLPGRSDV 540
  541 LVVVVSMLST APQPIRNIVF QSAVPKVMKV KLQPPSGTEL PAFNPIVHPS AITQVLLLAN 600
  601 PQKEKVRLRY KLTFTMGDQT YNEMGDVDQF PPPETWGSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 41.522879 ADP-ribosylation factor binding protein Gga1
    2 View Details [148..354] FFAS03 3.81 ADP-ribosylation factor binding protein Gga1
    3 View Details [355..506] MSA 1.336996 View MSA. No confident structure predictions are available.
    4 View Details [507..639] PSI-BLAST 26.30103 ADP-ribosylation factor binding protein Gga1 domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.44619623515316 bayes_pls_golite062009
  • binding
    		•  1.13238817008904 bayes_pls_golite062009
    2
    Term Confidence Notes
  • protein binding
    		•  1.13078327723547 bayes_pls_golite062009
  • binding
    		•  0.923235137045752 bayes_pls_golite062009
  • clathrin binding
    		•  0.456392002173877 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein binding
    		•  0.859533416004855 bayes_pls_golite062009
  • binding
    		•  0.575039289605127 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle