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View Structure Prediction Details

Protein: GGA1
Organism: Homo sapiens
Length: 639 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GGA1.

Description E-value Query
Range
Subject
Range
gi|109094103 - gi|109094103|ref|XP_001088573.1| PREDICTED: golgi associated, gamma adaptin ear containing, ARF bind...
0.0 [5..639] [1..635]
gi|47678517, gi|... - gi|47678517|emb|CAG30379.1| GGA1 [Homo sapiens], gi|169145162|emb|CAB63037.2| golgi associated, gamm...
HGNC:17842|MIM:6... - gamma adaptin ear containing, ARF binding protein 1
gi|109451898, gi... - gi|208967845|dbj|BAG72568.1| golgi associated, gamma adaptin ear containing, ARF binding protein 1 [...
0.0 [1..639] [1..656]
gi|114686307 - gi|114686307|ref|XP_001161444.1| PREDICTED: golgi associated, gamma adaptin ear containing, ARF bind...
0.0 [1..639] [1..636]
gi|73969169 - gi|73969169|ref|XP_538387.2| PREDICTED: similar to ADP-ribosylation factor binding protein GGA1 (Gol...
1.0E-99 [5..639] [1..632]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPAMEPETL EARINRATNP LNKELDWASI NGFCEQLNED FEGPPLATRL LAHKIQSPQE  60
   61 WEAIQALTVL ETCMKSCGKR FHDEVGKFRF LNELIKVVSP KYLGSRTSEK VKNKILELLY 120
  121 SWTVGLPEEV KIAEAYQMLK KQGIVKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 1jwfA
Description: ADP-ribosylation factor binding protein Gga1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.44619623515316 bayes_pls_golite062009
binding 1.13238817008904 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [148-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPKLPDDTTF PLPPPRPKNV IFEDEEKSKM LARLLKSSHP EDLRAANKLI KEMVQEDQKR  60
   61 MEKISKRVNA IEEVNNNVKL LTEMVMSHSQ GGAAAGSSED LMKELYQRCE RMRPTLFRLA 120
  121 SDTEDNDEAL AEILQANDNL TQVINLYKQL VRGEEVNGDA TAGSIPGSTS ALLDLSGLDL 180
  181 PPAGTTYPAM PTRPGEQASP EQPSASV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.81
Match: 1oxzA
Description: ADP-ribosylation factor binding protein Gga1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.13078327723547 bayes_pls_golite062009
binding 0.923235137045752 bayes_pls_golite062009
clathrin binding 0.456392002173877 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [355-506]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLLDDELMSL GLSDPTPPSG PSLDGTGWNS FQSSDATEPP APALAQAPSM ESRPPAQTSL  60
   61 PASSGLDDLD LLGKTLLQQS LPPESQQVRW EKQQPTPRLT LRDLQNKSSS CSSPSSSATS 120
  121 LLHTVSPEPP RPPQQPVPTE LSLASITVPL ES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [507-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKPSNILPVT VYDQHGFRIL FHFARDPLPG RSDVLVVVVS MLSTAPQPIR NIVFQSAVPK  60
   61 VMKVKLQPPS GTELPAFNPI VHPSAITQVL LLANPQKEKV RLRYKLTFTM GDQTYNEMGD 120
  121 VDQFPPPETW GSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.30103
Match: 1na8A
Description: ADP-ribosylation factor binding protein Gga1 domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 0.859533416004855 bayes_pls_golite062009
binding 0.575039289605127 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle