Protein Overview: KLHDC4

General Information:
Name(s) found:	KLHDC4 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|74730447\|sp\|Q8TBB5.1\|KLDC4_HUMAN RecName: Full=Kelch domain-containing protein 4 [NCBI NR] gi\|21314675\|ref\|NP_060036.2\| kelch domain containing 4 [Homo sapiens] [NCBI NR] gi\|18606155\|gb\|AAH22969.1\| Kelch domain containing 4 [Homo sapiens] [NCBI NR] gi\|119615784\|gb\|EAW95378.1\| kelch domain containing 4, isoform CRA_b [Homo sapiens] [NCBI NR] gi\|119615783\|gb\|EAW95377.1\| kelch domain containing 4, isoform CRA_b [Homo sapiens] [NCBI NR] kelch domain containing 4 [HGNC (HUGO)] Kelch domain-containing protein 4 OS=Homo sapiens GN=KLHDC4 PE=1 SV=1 [Swiss-Prot] Hypothetical protein [hmr_yeast5_DM3-1_pombe.fasta] hypothetical protein DKFZp434G0522 [HMR_022704.fasta] kelch domain containing 4 [Homo sapiens]gi\|18606155\|gb\|AAH22969.1\| Kelch domain containing 4 [Homo sapiens] [nrdb_11152004_Chlamydomonas] Tax_Id=9606 Splice Isoform 1 of Kelch domain-containing protein 4 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_017566) hypothetical protein DKFZp434G0522 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] kelch domain containing 4 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Kelch domain containing 4 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] hypothetical protein DKFZp434G0522 [Homo sapiens] [human-NCBI-042104-rand.fasta] Kelch domain-containing protein 4 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] kelch domain containing 4, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Kelch domain containing 4 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of Kelch domain-containing protein 4 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 KELCH DOMAIN CONTAINING 4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=KLHDC4 Isoform 1 of Kelch domain-containing protein 4 [human-ipi-250309-contam.fasta] IPI:IPI00152182.1\|SWISS-PROT:Q8TBB5-1\|TREMBL:Q9H863\|ENSEMBL:ENSP00000270583\|REFSEQ:NP_060036\|H-INV:HIT000039686\|VEGA:OTTHUMP00000080441;OTTHUMP00000175012 Tax_Id=9606 Gene_Symbol=KLHDC4 Isoform 1 of Kelch domain-containing protein 4 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=KLHDC4 Isoform 1 of Kelch domain-containing protein 4 ENSG00000104731 IPI00642250 IPI00152182 IPI00304958 IPI00297861 IPI00646806 IPI00643644 IPI00829677 [drosphohumanreversed.fasta] Q8TBB5;Q96F29;Q9BVN3; RecName: Full=Kelch domain-containing protein 4; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of Kelch domain-containing protein 4 OS=Homo sapiens GN=KLHDC4 [011711_HMR.fasta] IPI:IPI00152182.1\|SWISS-PROT:Q8TBB5-1\|TREMBL:D3DUN5;Q9H863\|ENSEMBL:ENSP00000270583\|REFSEQ:NP_060036\|H-INV:HIT000039686\|VEGA:OTTHUMP00000080441;OTTHUMP00000175012 Tax_Id=9606 Gene_Symbol=KLHDC4 Isoform 1 of Kelch domain-containing protein 4 [ipi.HUMAN.fasta.20100406] GeneSymbol=KLHDC4 Synonyms=DKFZp434G0522\|FLJ00104 kelch domain-containing protein 4 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00152182.1\|SWISS-PROT:Q8TBB5-1\|TREMBL:Q9H863\|ENSEMBL:ENSP00000270583\|REFSEQ:NP_060036\|H-INV:HIT000039686\|VEGA:OTTHUMP00000175012 Tax_Id=9606 Gene_Symbol=KLHDC4 Isoform 1 of Kelch domain-containing protein 4 [ipi.HUMAN.20110912.fasta] Kelch domain-containing protein 4 GN=KLHDC4 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	520 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKGKKEKK GRGAEKTAAK MEKKVSKRSR KEEEDLEALI AHFQTLDAKR TQTVELPCPP  60
   61 PSPRLNASLS VHPEKDELIL FGGEYFNGQK TFLYNELYVY NTRKDTWTKV DIPSPPPRRC 120
  121 AHQAVVVPQG GGQLWVFGGE FASPNGEQFY HYKDLWVLHL ATKTWEQVKS TGGPSGRSGH 180
  181 RMVAWKRQLI LFGGFHESTR DYIYYNDVYA FNLDTFTWSK LSPSGTGPTP RSGCQMSVTP 240
  241 QGGIVVYGGY SKQRVKKDVD KGTRHSDMFL LKPEDGREDK WVWTRMNPSG VKPTPRSGFS 300
  301 VAMAPNHQTL FFGGVCDEEE EESLSGEFFN DLYFYDATRN RWFEGQLKGP KSEKKKRRRG 360
  361 RKEEPEGGSR PACGGAGTQG PVQLVKEVVA EDGTVVTIKQ VLTAPGSAGQ PRSEDEDSLE 420
  421 EAGSPAPGPC PRSNAMLAVK HGVLYVYGGM FEAGDRQVTL SDLHCLDLHR MEAWKALVEM 480
  481 DPETQEWLEE TDSEEDSEEV EGAEGGVDDE DSGEESGAED

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..353]	PSI-BLAST	41.522879	Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2
2	View Details	[354..520]	FFAS03	2.63	No description for 2dyhA was found.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: KLHDC4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: