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Protein Overview: KLHDC4

General Information:
Name(s) found: KLHDC4 [HGNC (HUGO)]
Description(s) found:
Found 30 descriptions.
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  • kelch domain containing 4 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKGKKEKK GRGAEKTAAK MEKKVSKRSR KEEEDLEALI AHFQTLDAKR TQTVELPCPP  60
   61 PSPRLNASLS VHPEKDELIL FGGEYFNGQK TFLYNELYVY NTRKDTWTKV DIPSPPPRRC 120
  121 AHQAVVVPQG GGQLWVFGGE FASPNGEQFY HYKDLWVLHL ATKTWEQVKS TGGPSGRSGH 180
  181 RMVAWKRQLI LFGGFHESTR DYIYYNDVYA FNLDTFTWSK LSPSGTGPTP RSGCQMSVTP 240
  241 QGGIVVYGGY SKQRVKKDVD KGTRHSDMFL LKPEDGREDK WVWTRMNPSG VKPTPRSGFS 300
  301 VAMAPNHQTL FFGGVCDEEE EESLSGEFFN DLYFYDATRN RWFEGQLKGP KSEKKKRRRG 360
  361 RKEEPEGGSR PACGGAGTQG PVQLVKEVVA EDGTVVTIKQ VLTAPGSAGQ PRSEDEDSLE 420
  421 EAGSPAPGPC PRSNAMLAVK HGVLYVYGGM FEAGDRQVTL SDLHCLDLHR MEAWKALVEM 480
  481 DPETQEWLEE TDSEEDSEEV EGAEGGVDDE DSGEESGAED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..353] PSI-BLAST 41.522879 Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2
    2 View Details [354..520] FFAS03 2.63 No description for 2dyhA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle