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Protein Overview: EEF1B2

General Information:
Name(s) found: EEF1B2 [HGNC (HUGO)]
Description(s) found:
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  • gi|83376130|ref|NP_001032752.1| eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • gi|62822514|gb|AAY15062.1| unknown [Homo sapiens] [NCBI NR]
  • gi|48145767|emb|CAG33106.1| EEF1B2 [Homo sapiens] [NCBI NR]
  • gi|45709232|gb|AAH67787.1| Eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • gi|4503477|ref|NP_001950.1| eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • gi|31135|emb|CAA43063.1| elongation factor 1-beta [Homo sapiens] [NCBI NR]
  • gi|31100|emb|CAA43019.1| elongation factor-1-beta [Homo sapiens] [NCBI NR]
  • gi|30582997|gb|AAP35742.1| eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • pir||S25432 translation elongation factor eEF-1 beta chain - human [NCBI NR]
  • gi|158257252|dbj|BAF84599.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|13436266|gb|AAH04931.1| Eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • gi|12652911|gb|AAH00211.1| Eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • gi|119590788|gb|EAW70382.1| eukaryotic translation elongation factor 1 beta 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119590787|gb|EAW70381.1| eukaryotic translation elongation factor 1 beta 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119163|sp|P24534.3|EF1B_HUMAN RecName: Full=Elongation factor 1-beta; Short=EF-1-beta [NCBI NR]
  • gi|11136628|ref|NP_066944.1| eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI NR]
  • eukaryotic translation elongation factor 1 beta 2 [HGNC (HUGO)]
  • Elongation factor 1-beta OS=Homo sapiens GN=EEF1B2 PE=1 SV=3 [Swiss-Prot]
  • eukaryotic translation elongation factor 1 beta 2; eukaryotic translation elongation factor 1 beta 1 [HMR_022704.fasta]
  • eukaryotic translation elongation factor 1 beta 2 [Homo sapiens]gi|4503477|ref|NP_001950.1| eukaryotic translation elongation factor 1 beta 2 [Homo sapiens]gi|30582997|gb|AAP35742.1| eukaryotic translation elongation factor 1 beta 2 [Homo sapiens]gi|45 [nrdb_11152004_Chlamydomonas]
  • Elongation factor 1-beta (EF-1-beta) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • (NM_021121) eukaryotic translation elongation factor 1 beta 2; eukaryotic translation elongation factor 1 beta 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • (NM_001959) eukaryotic translation elongation factor 1 beta 2; eukaryotic translation elongation factor 1 beta 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Eukaryotic translation Elongation factor 1 bEta 2 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • eukaryotic translation elongation factor 1 beta 2; eukaryotic translation elongation factor 1 beta 1 [Homo sapiens] [HumanGallus06162005.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • eukaryotic translation elongation factor 1 beta 2, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Eukaryotic translation elongation factor 1 beta 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unknown [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • EEF1B2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • elongation factor 1-beta [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • elongation factor-1-beta [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 BETA 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=EEF1B2 Elongation factor 1-beta [human-ipi-250309-contam.fasta]
  • IPI:IPI00178440.3|SWISS-PROT:P24534|TREMBL:A4D1M6;A8K795|ENSEMBL:ENSP00000236957;ENSP00000376055;ENSP00000376056|REFSEQ:NP_001032752;NP_001950;NP_066944|H-INV:HIT000322412|VEGA:OTTHUMP00000163805;OTTHUMP00000206335 Tax_Id=9606 Gene_Symbol=EEF1B2 Elongatio [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Elongation factor 1-beta [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=EEF1B2 Elongation factor 1-beta ENSG00000114942 IPI00178440 [drosphohumanreversed.fasta]
  • P24534;A8K795;Q6IBH9; RecName: Full=Elongation factor 1-beta; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Elongation factor 1-beta OS=Homo sapiens GN=EEF1B2 [011711_HMR.fasta]
  • IPI:IPI00178440.3|SWISS-PROT:P24534|TREMBL:A4D1M6|ENSEMBL:ENSP00000236957;ENSP00000376055;ENSP00000376056|REFSEQ:NP_001032752;NP_001950;NP_066944|H-INV:HIT000322412|VEGA:OTTHUMP00000163805;OTTHUMP00000206335 Tax_Id=9606 Gene_Symbol=EEF1B2 Elongation factor 1-beta [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=EEF1B2 Synonyms=EEF1B|EEF1B1|EF1B elongation factor 1-beta [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00178440.3|SWISS-PROT:P24534|TREMBL:A4D1M6|ENSEMBL:ENSP00000236957;ENSP00000376055;ENSP00000376056|REFSEQ:NP_001032752;NP_001950;NP_066944|H-INV:HIT000322412|VEGA:OTTHUMP00000163805;OTTHUMP00000206335 Tax_Id=9606 Gene_Symbol=SNORA41;EEF1B2 Elongation factor 1-beta [ipi.HUMAN.20110912.fasta]
  • Elongation factor 1-beta GN=EEF1B2 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=SNORA41;EEF1B2 Elongation factor 1-beta [human-ipi-270911-contam-BSA.fasta]
  • Eukaryotic translation elongation factor 1 beta 2, isoform CRA_a OS=Homo sapiens GN=EEF1B2 PE=3 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 225 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFGDLKSPA GLQVLNDYLA DKSYIEGYVP SQADVAVFEA VSSPPPADLC HALRWYNHIK  60
   61 SYEKEKASLP GVKKALGKYG PADVEDTTGS GATDSKDDDD IDLFGSDDEE ESEEAKRLRE 120
  121 ERLAQYESKK AKKPALVAKS SILLDVKPWD DETDMAKLEE CVRSIQADGL VWGSSKLVPV 180
  181 GYGIKKLQIQ CVVEDDKVGT DMLEEQITAF EDYVQSMDVA AFNKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] PSI-BLAST 3.522879 Glutathione S-transferase 1-6 from Anopheles dirus species B
    2 View Details [132..225] PSI-BLAST 39.69897 SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.65945313523198 bayes_pls_golite062009
  • binding
    		•  1.45526122320486 bayes_pls_golite062009
  • transferase activity
    		•  1.05573069897577 bayes_pls_golite062009
  • catalytic activity
    		•  0.963623964325467 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.46030380837916 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  0.44372379417457 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385619646192102 bayes_pls_golite062009
  • glutathione transferase activity
    		•  0.20688408808374 bayes_pls_golite062009
  • DNA binding
    		•  0.175092771820973 bayes_pls_golite062009
  • receptor binding
    		•  0.0497559408754589 bayes_pls_golite062009
    2
    Term Confidence Notes
  • translation elongation factor activity
    		•  12.3173391557088 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  7.81664120156021 bayes_pls_golite062009
  • translation regulator activity
    		•  7.77673515271111 bayes_pls_golite062009
  • actin binding
    		•  3.32293986705361 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.89895269798148 bayes_pls_golite062009
  • binding
    		•  2.83703195704118 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.61354904861592 bayes_pls_golite062009
  • protein binding
    		•  1.74079757896683 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.669814437561164 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.651746786837234 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.555069882515023 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.260738180200771 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle