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Protein Overview: SMARCC2

General Information:
Name(s) found: SMARCC2 [HGNC (HUGO)]
Description(s) found:
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  • gi|57012959|sp|Q8TAQ2.1|SMRC2_HUMAN RecName: Full=SWI/SNF complex subunit SMARCC2; AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; AltName: Full=SWI/SNF complex 170 kDa subunit; AltName: Full=BR [NCBI NR]
  • gi|21237805|ref|NP_003066.2| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens] [NCBI NR]
  • gi|20072796|gb|AAH26222.1| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [Homo sapiens] [NCBI NR]
  • gi|119617313|gb|EAW96907.1| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119617312|gb|EAW96906.1| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, isoform CRA_a [Homo sapiens] [NCBI NR]
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [HGNC (HUGO)]
  • SWI/SNF complex subunit SMARCC2 OS=Homo sapiens GN=SMARCC2 PE=1 SV=1 [Swiss-Prot]
  • Similar to SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [hmr_yeast5_DM3-1_pombe.fasta]
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a; mammalian chromatin remodeling complex BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; SWI3-like protein; SWI/SNF complex 170 kDa subunit [HMR_022704.fasta]
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens]gi|20072796|gb|AAH26222.1| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2, isoform a [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_003075) SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2, isoform a; mammalian chromatin remodeling complex BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; SWI3-like protein; SWI/SNF complex 170 kDa [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a; mammalian chromatin remodeling complex BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; SWI3-like protein; SWI/SNF complex 170 kDa subunit [Homo [HumanGallus06162005.fasta]
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN C2, ISOFORM A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SMARCC2 Isoform 1 of SWI/SNF complex subunit SMARCC2 [human-ipi-250309-contam.fasta]
  • IPI:IPI00216047.3|SWISS-PROT:Q8TAQ2-1|ENSEMBL:ENSP00000267064|REFSEQ:NP_003066|H-INV:HIT000040150|VEGA:OTTHUMP00000168107 Tax_Id=9606 Gene_Symbol=SMARCC2 Isoform 1 of SWI/SNF complex subunit SMARCC2 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=SMARCC2 Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 ENSG00000139613 IPI00216047 IPI00150057 IPI00791889 IPI00789967 IPI00793183 IPI00791331 IPI00793163 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=SMARCC2 Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • SWI/SNF complex subunit SMARCC2 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q8TAQ2;Q92923;Q96E12;Q96GY4; RecName: Full=SWI/SNF complex subunit SMARCC2; AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; AltName: Full=SWI/SNF complex 170 kDa subunit; AltName: Full=BRG1-associated factor 170; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of SWI/SNF complex subunit SMARCC2 OS=Homo sapiens GN=SMARCC2 [011711_HMR.fasta]
  • GeneSymbol=SMARCC2 Synonyms=BAF170|CRACC2|DKFZp313D0632|Rsc8 SWI/SNF complex subunit SMARCC2 isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00216047.3|SWISS-PROT:Q8TAQ2-1|ENSEMBL:ENSP00000267064|REFSEQ:NP_003066|H-INV:HIT000040150 Tax_Id=9606 Gene_Symbol=SMARCC2 Isoform 1 of SWI/SNF complex subunit SMARCC2 [ipi.HUMAN.20110912.fasta]
  • SWI/SNF complex subunit SMARCC2 GN=SMARCC2 [Doctor+uniprot-HUMAN-120911.fasta]
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, isoform CRA_a OS=Homo sapiens GN=SMARCC2 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 1214 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVRKKDGGP NVKYYEAADT VTQFDNVRLW LGKNYKKYIQ AEPPTNKSLS SLVVQLLQFQ  60
   61 EEVFGKHVSN APLTKLPIKC FLDFKAGGSL CHILAAAYKF KSDQGWRRYD FQNPSRMDRN 120
  121 VEMFMTIEKS LVQNNCLSRP NIFLCPEIEP KLLGKLKDII KRHQGTVTED KNNASHVVYP 180
  181 VPGNLEEEEW VRPVMKRDKQ VLLHWGYYPD SYDTWIPASE IEASVEDAPT PEKPRKVHAK 240
  241 WILDTDTFNE WMNEEDYEVN DDKNPVSRRK KISAKTLTDE VNSPDSDRRD KKGGNYKKRK 300
  301 RSPSPSPTPE AKKKNAKKGP STPYTKSKRG HREEEQEDLT KDMDEPSPVP NVEEVTLPKT 360
  361 VNTKKDSESA PVKGGTMTDL DEQEDESMET TGKDEDENST GNKGEQTKNP DLHEDNVTEQ 420
  421 THHIIIPSYA AWFDYNSVHA IERRALPEFF NGKNKSKTPE IYLAYRNFMI DTYRLNPQEY 480
  481 LTSTACRRNL AGDVCAIMRV HAFLEQWGLI NYQVDAESRP TPMGPPPTSH FHVLADTPSG 540
  541 LVPLQPKTPQ QTSASQQMLN FPDKGKEKPT DMQNFGLRTD MYTKKNVPSK SKAAASATRE 600
  601 WTEQETLLLL EALEMYKDDW NKVSEHVGSR TQDECILHFL RLPIEDPYLE DSEASLGPLA 660
  661 YQPIPFSQSG NPVMSTVAFL ASVVDPRVAS AAAKSALEEF SKMKEEVPTA LVEAHVRKVE 720
  721 EAAKVTGKAD PAFGLESSGI AGTTSDEPER IEESGNDEAR VEGQATDEKK EPKEPREGGG 780
  781 AIEEEAKEKT SEAPKKDEEK GKEGDSEKES EKSDGDPIVD PEKEKEPKEG QEEVLKEVVE 840
  841 SEGERKTKVE RDIGEGNLST AAAAALAAAA VKAKHLAAVE ERKIKSLVAL LVETQMKKLE 900
  901 IKLRHFEELE TIMDREREAL EYQRQQLLAD RQAFHMEQLK YAEMRARQQH FQQMHQQQQQ 960
  961 PPPALPPGSQ PIPPTGAAGP PAVHGLAVAP ASVVPAPAGS GAPPGSLGPS EQIGQAGSTA1020
 1021 GPQQQQPAGA PQPGAVPPGV PPPGPHGPSP FPNQQTPPSM MPGAVPGSGH PGVAGNAPLG1080
 1081 LPFGMPPPPP PPAPSIIPFG SLADSISINL PAPPNLHGHH HHLPFAPGTL PPPNLPVSMA1140
 1141 NPLHPNLPAT TTMPSSLPLG PGLGSAAAQS PAIVAAVQGN LLPSASPLPD PGTPLPPDPT1200
 1201 APSPGTVTPV PPPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..216] deduced N/A No confident structure predictions are available.
    2 View Details [217..413] deduced N/A No confident structure predictions are available.
    3 View Details [414..526] PSI-BLAST 41.39794 Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
    4 View Details [527..693] FFAS03 2.83 No description for 2nogA was found.
    5 View Details [694..1214] PSI-BLAST 42.39794 No description for 1y0fB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle