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Protein Overview: OSBPL6

General Information:
Name(s) found: OSBPL6 [HGNC (HUGO)]
Description(s) found:
Found 32 descriptions.
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  • oxysterol binding protein-like 6 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 934 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDEKGISP AHKTSTPTHR SASSSTSSQR DSRQSIHILE RTASSSTEPS VSRQLLEPEP  60
   61 VPLSKEADSW EIIEGLKIGQ TNVQKPDKHE GFMLKKRKWP LKGWHKRFFV LDNGMLKYSK 120
  121 APLDIQKGKV HGSIDVGLSV MSIKKKARRI DLDTEEHIYH LKVKSQDWFD AWVSKLRHHR 180
  181 LYRQNEIVRS PRDASFHIFP STSTAESSPA ANVSVMDGKM QPNSFPWQSP LPCSNSLPAT 240
  241 CTTGQSKVAA WLQDSEEMDR CAEDLAHCQS NLVELSKLLQ NLEILQRTQS APNFTDMQAN 300
  301 CVDISKKDKR VTRRWRTKSV SKDTKIQLQV PFSATMSPVR LHSSNPNLCA DIEFQTPPSH 360
  361 LTDPLESSTD YTKLQEEFCL IAQKVHSLLK SAFNSIAIEK EKLKQMVSEQ DHSKGHSTQM 420
  421 ARLRQSLSQA LNQNAELRSR LNRIHSESII CDQVVSVNII PSPDEAGEQI HVSLPLSQQV 480
  481 ANESRLSMSE SVSEFFDAQE VLLSASSSEN EASDDESYIS DVSDNISEDN TSVADNISRQ 540
  541 ILNGELTGGA FRNGRRACLP APCPDTSNIN LWNILRNNIG KDLSKVSMPV ELNEPLNTLQ 600
  601 HLCEEMEYSE LLDKASETDD PYERMVLVAA FAVSGYCSTY FRAGSKPFNP VLGETYECIR 660
  661 EDKGFRFFSE QVSHHPPISA CHCESKNFVF WQDIRWKNKF WGKSMEILPV GTLNVMLPKY 720
  721 GDYYVWNKVT TCIHNILSGR RWIEHYGEVT IRNTKSSVCI CKLTFVKVNY WNSNMNEVQG 780
  781 VVIDQEGKAV YRLFGKWHEG LYCGVAPSAK CIWRPGSMPT NYELYYGFTR FAIELNELDP 840
  841 VLKDLLPPTD ARFRPDQRFL EEGNLEAAAS EKQRVEELQR SRRRYMEENN LEHIPKFFKK 900
  901 VIDANQREAW VSNDTYWELR KDPGFSKVDS PVLW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] PSI-BLAST 16.39794 Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
    2 View Details [211..415] MSA 1.599982 View MSA. No confident structure predictions are available.
    3 View Details [416..557] deduced N/A No confident structure predictions are available.
    4 View Details [558..934] PSI-BLAST 80.69897 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.42470476396787 bayes_pls_golite062009
  • protein binding
    		•  2.1446140694885 bayes_pls_golite062009
  • receptor binding
    		•  0.3173431866346 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • oxysterol binding
    		•  2.56824234952236 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
    		• 0.35288515581255 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle