Protein Overview: RBD2

General Information:
Name(s) found:	RBD2 / YPL246C [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	262 amino acids
Gene Ontology:
Cellular Component:	Golgi apparatus [IDA] COPI-coated vesicle [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNWKSYVFPG GHPPAALTTG LVVFLTAIYL LSFIFALRED LSLAPESLFK LQMSRLSLYP  60
   61 LIHLSLPHLL FNVLAIWAPL NLFEETHGTV YTGVFLNLSA LFAGILYCLL GKLLYPEALV 120
  121 AGASGWCFTL FAYYSFKESQ IRPRTRIFRT DYSIPTLYTP LVLLVAIAVV IPGSSFWGHF 180
  181 FGLCVGYAIG YKESWFNKIT PPGWIITKIE KSLDGLIRLI PWGIKYYRDE DIDRTKDYEP 240
  241 LMSTETPLPL HNDNSGTVLG TA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	VAM7	RBD2	2	Uetz P, et al. (2000)
View Screen	YPT35	RBD2	2	Uetz P, et al. (2000)
View Screen	LAS17	RBD2	2	Drees BL, et al. (2001)
View Screen	SNX3	RBD2	2	Unpublished Fields Lab Data
View Screen	YPT1	RBD2	2	Uetz P, et al. (2000)
View Screen	RAD6	RBD2	1	Unpublished Fields Lab Data
View Screen	RRB1	RBD2	1	Unpublished Fields Lab Data
View Screen	MPC54	RBD2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	RBD2 and ANP1	Huh WK, et al. (2003)
View Data	RBD2 and COP1	Huh WK, et al. (2003)
View Data	RBD2	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..262]	Pfam	48.187087	Rhomboid family No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
catalytic activity	0.545407789079971	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2