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Protein Overview: RNY1

General Information:
Name(s) found: RNY1 / YPL123C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 434 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDALink to PubMed article]
    Biological Process: cell morphogenesis [IMPLink to PubMed article]
    Molecular Function: endoribonuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLKNLHSLL QLPIFSNGAD KGIEPNCPIN IPLSCSNKTD IDNSCCFEYP GGIFLQTQFW  60
   61 NYFPSKNDLN ETELVKELGP LDSFTIHGLW PDNCHGGYQQ FCNRSLQIDD VYYLLHDKKF 120
  121 NNNDTSLQIS GEKLLEYLDL YWKSNNGNHE SLWIHEFNKH GTCISTIRPE CYTEWGANSV 180
  181 DRKRAVYDYF RITYNLFKKL DTFSTLEKNN IVPSVDNSYS LEQIEAALSK EFEGKKVFIG 240
  241 CDRHNSLNEV WYYNHLKGSL LSEMFVPMDS LAIRTNCKKD GIKFFPKGYV PTFRRRPNKG 300
  301 ARYRGVVRLS NINNGDQMQG FLIKNGHWMS QGTPANYELI KSPYGNYYLR TNQGFCDIIS 360
  361 SSSNELVCKF RNIKDAGQFD FDPTKGGDGY IGYSGNYNWG GDTYPRRRNQ SPIFSVDDEQ 420
  421 NSKKYKFKLK FIKN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 233.69897 Ribonuclease Rh
    2 View Details [300..434] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.56

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle