Protein Overview: MEI5

General Information:
Name(s) found:	MEI5 / YPL121C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6325136\|ref\|NP_015204.1\| Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p; Mei5p [Saccharomyces cerevisiae] [NCBI NR] gi\|2507061\|sp\|P32489.2\|MEI5_YEAST RecName: Full=Meiosis protein 5 [NCBI NR] pir\|\|S62001 MEI5 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1163093\|gb\|AAB68241.1\| Mei5p: Meiotic protein required for synapsis and meiotic recombination [Saccharomyces cerevisiae] [NCBI NR] Meiosis protein 5 OS=Saccharomyces cerevisiae GN=MEI5 PE=1 SV=2 [Swiss-Prot] MEI5 Meiotic protein [mips] Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p [SGD] (P32489) Meiosis protein 5 [4932.FASTACCERV.txt] Chr XVI from 321629-320961, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XVI from 320961-321629, reverse complement [yeastorf3.fasta] MEI5, Chr XVI from 320961-321629, reverse complement [yeast_orfs2] MEI5 SGDID:S0006042, Chr XVI from 321629-320961, reverse complement, Verified ORF [yeastflysequest.fasta] Mei5p [Saccharomyces cerevisiae]gi\|2507061\|sp\|P32489\|MEI5_YEAST Meiosis protein 5gi\|2132336\|pir\|\|S62001 MEI5 protein - yeast (Saccharomyces cerevisiae)gi\|1163093\|gb\|AAB68241.1\| Mei5p,Lph6p [nrdb_11152004_Chlamydomonas] MEI5 SGDID:S000006042, Chr XVI from 321629-320961, reverse complement, Verified ORF, "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p; Mei5p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Meiosis protein 5 [nr-271106-contam.fasta] Mei5p: Meiotic protein required for synapsis and meiotic recombination [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Meiosis protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MEI5 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] MEI5 SGDID:S000006042, Chr XVI from 321630-320962, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" [yeast-030211-contam.fasta] MEI5 SGDID:S000006042, Chr XVI from 321630-320962, Genome Release 64-2-1, reverse complement, Verified ORF, "Meiosis-specific protein involved in meiotic recombination; involved in DMC1-dependent meiotic recombination; forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" [20141208_orf_trans.fasta] YPL121C SGDID:S000006042, Chr XVI from 321630-320962, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	222 amino acids
Gene Ontology:
Cellular Component:	condensed nuclear chromosome [IDA ]
Biological Process:	meiotic DNA recombinase assembly [IMP ] reciprocal meiotic recombination [IMP ]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHNQEEWLDK DKTLVNEEEN TCINHSYTKK DTNNYRVGKS GIKDLKKPTN QKEIAIKNRE  60
   61 LTKQLTLLRQ ENNHLQQACK ILSENKIIEN RKSIEKWRTI CEMELSFILN STLIKINRMG 120
  121 GYKDFLEKEM EAKKRRLEYQ IDNGMEDQIC EIKESDDFRQ LSEVEKQEWE SQMNEQLKEL 180
  181 EKKKIAELEK LNKVLHDSEG KDFGMAELCT RLKLDYSLIF PQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SWI5	MEI5	2	Unpublished Fields Lab Data
View Screen	THP2	MEI5	2	Unpublished Fields Lab Data
View Screen	SPP382	MEI5	2	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..222]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2