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Protein Overview: FSH3

General Information:
Name(s) found: FSH3 / YOR280C [SGD]
Description(s) found:
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  • gi|68052243|sp|Q99369.1|FSH3_YEAST RecName: Full=Family of serine hydrolases 3 [NCBI NR]
  • gi|6324854|ref|NP_014923.1| Serine hydrolase; sequence is similar to Fsh1p and Fsh2p; Fsh3p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S67182 hypothetical protein YOR280c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420625|emb|CAA99506.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1279705|emb|CAA61785.1| hypothetical dihydrofolate reductase [Saccharomyces cerevisiae] [NCBI NR]
  • Family of serine hydrolases 3 OS=Saccharomyces cerevisiae GN=FSH3 PE=1 SV=1 [Swiss-Prot]
  • FSH3 Serine hydrolase/alpha/beta hydrolase subset, localizes to both the nucleus and cytoplasm [mips]
  • Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2 [SGD]
  • >Q99369 (Q99369) Hypothetical dihydrofolate reductase [4932.FASTACCERV.txt]
  • Chr XV from 845789-844989, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 844988-845788, reverse complement [yeastorf3.fasta]
  • Chr XV from 844989-845789, reverse complement [yeastorf4.fasta]
  • YOR280C, Chr XV from 844988-845788, reverse complement [yeast_orfs2]
  • FSH3 SGDID:S0005806, Chr XV from 845789-844989, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Fsh3p [Saccharomyces cerevisiae]gi|1279705|emb|CAA61785.1| hypothetical dihydrofolate reductase [Saccharomyces cerevisiae]gi|1420625|emb|CAA99506.1| unnamed protein product [Saccharomyces cerevisiae]gi|2132110|pir||S67182 hypothetical protein YOR280c - [nrdb_11152004_Chlamydomonas]
  • (Q99369) Hypothetical dihydrofolate reductase (S.cerevisiae chromosome XV reading frame ORF YOR280c) [cerv4932.FASTAC]
  • FSH3 SGDID:S000005806, Chr XV from 845789-844989, reverse complement, Verified ORF, "Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh1p and Fsh3p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • FSH3 SGDID:S000005806, Chr XV from 845791-844991, reverse complement, Verified ORF, "Serine hydrolase; sequence is similar to Fsh1p and Fsh2p" [yeast-contam.fasta]
  • FSH3 SGDID:S000005806, Chr XV from 845791-844991, reverse complement, Verified ORF, "Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tum [yeast-200209-contam.fasta]
  • Serine hydrolase; sequence is similar to Fsh1p and Fsh2p; Fsh3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Family of serine hydrolases 3 [nr-271106-contam.fasta]
  • hypothetical dihydrofolate reductase [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • FSH3 SGDID:S000005806, Chr XV from 845791-844991, reverse complement, Verified ORF, "Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Family of serine hydrolases 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FSH3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • FSH3 SGDID:S000005806, Chr XV from 845792-844992, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2" [yeast-030211-contam.fasta]
  • FSH3 SGDID:S000005806, Chr XV from 845792-844992, Genome Release 64-2-1, reverse complement, Verified ORF, "Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2" [20141208_orf_trans.fasta]
  • TR7722|c0_g1_i1|g.5362 ORF TR7722|c0_g1_i1|g.5362 TR7722|c0_g1_i1|m.5362 type:complete len:267 (+) TR7722|c0_g1_i1:138-938(+) [Y12_S_cerevisiae-Sep2015-contam.fasta]
  • TR3798|c0_g1_i1|g.2572 ORF TR3798|c0_g1_i1|g.2572 TR3798|c0_g1_i1|m.2572 type:complete len:267 (+) TR3798|c0_g1_i1:220-1020(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta]
  • YOR280C SGDID:S000005806, Chr XV from 845792-844992, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • asmbl_2860|g.2022 ORF asmbl_2860|g.2022 asmbl_2860|m.2022 type:complete len:267 (+) asmbl_2860:220-1020(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta]
  • Family of serine hydrolases 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FSH3 PE=2 SV=1 [uniprot_sprot.fasta.20160308]
  • ID=asmbl_2864|g.1748 ORF ID=asmbl_2864|g.1748 ID=asmbl_2864|m.1748 type:complete len:267 (+) ID=asmbl_2864:220-1020(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
  • ID=asmbl_2971|g.1745 ORF ID=asmbl_2971|g.1745 ID=asmbl_2971|m.1745 type:complete len:267 (+) ID=asmbl_2971:138-938(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 266 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: serine hydrolase activity [IDALink to PubMed article][RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKKKVLML HGFVQSDKIF SAKTGGLRKN LKKLGYDLYY PCAPHSIDKK ALFQSESEKG  60
   61 RDAAKEFNTS ATSDEVYGWF FRNPESFNSF QIDQKVFNYL RNYVLENGPF DGVIGFSQGA 120
  121 GLGGYLVTDF NRILNLTDEQ QPALKFFISF SGFKLEDQSY QKEYHRIIQV PSLHVRGELD 180
  181 EVVAESRIMA LYESWPDNKR TLLVHPGAHF VPNSKPFVSQ VCNWIQGITS KEGQEHNAQP 240
  241 EVDRKQFDKP QLEDDLLDMI DSLGKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..266] PSI-BLAST 50.30103 Acyl protein thioesterase 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • binding
    		•  0.978846093152455 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.603999106175838 bayes_pls_golite062009
  • structural molecule activity
    		•  0.165872846726831 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.0264147222103929 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle