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Protein Overview: SWT1

General Information:
Name(s) found: SWT1 / YOR166C [SGD]
Description(s) found:
Found 31 descriptions.
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  • RNA endoribonuclease involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDEKRAFPK GNNHIRSETF NGSVSHKISE SIKDIASLRP HGKYTVQDID NIIASTSSHE  60
   61 NRGQSGDSNG CINHDEEGDI PMCDLNDESD VEMISEYLSS QREMEAQSVA NYMPKINDDL 120
  121 PLLNPPTLKT AFVVDTNFII SHLNTLEKLR SLSSTYHHLI IVPTTVIQEL DGLKKSPDIA 180
  181 RDNDDTTNQE HDRTIGTLAR WGNDWIYKNL ANLDSGLIGQ KLKQSLNPGS LKDDSILDCC 240
  241 LYFKEILNCF VILLSNDKNL CTKALTEDIL TVSFRKNMDA KIIAMRAYEE NQLRFANLRD 300
  301 STVNNFDQNV TSYAHIPGIE TPPLQFDKVS QNVFEQVKET IFFAIDHTLR KEYGEDIGFI 360
  361 DYNPDKLTTI ENASNYIYLF WVSVFSELFT CSKIKKNEWK SLPTVLKSKP TNLNDLRTFE 420
  421 QFWETVLHFL FSKFTNEEKQ SLEKQIHEWK TSINAIST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] deduced N/A No confident structure predictions are available.
    2 View Details [113..317] MSA 18.040981 View MSA. No confident structure predictions are available.
    3 View Details [318..458] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle