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Protein Overview: SMP3

General Information:
Name(s) found: SMP3 / YOR149C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Alpha 1,2-mannosyltransferase involved in glycosyl phosphatidyl inositol (GPI) biosynthesis; required for addition of the fourth, side branching mannose to the GPI core structure [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 516 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [TASLink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IMPLink to PubMed article]
    plasmid maintenance [IMPLink to PubMed article]
    Molecular Function: alpha-1,2-mannosyltransferase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRYQWWLYL VYAIGLMLCL GPSYIHPDEH FQCIEILAMQ FMKVKGTIPW EFKSKFAARS  60
   61 YGPLLLVYGP LFTILESFPE IQDNPALILY SMRLQNYVMY LLCYHFLIPK LIRDERKAVQ 120
  121 FMQKSLLLTS YVTWTYQTHT FSNSIETLAL ISTLTVMEDM VNEKNIQRSN FKNSVILGLI 180
  181 FSFGVFNRVT FPAFIFLPCL ILFWKFYRVH WKSFSLLLLS FSFSSCLFVL IDTNIYNNGK 240
  241 GFVITPLNNL KYNLNVQNLQ VHGLHPRYTH LLVNLPQIVG PVLLLAIFSG YKLDKLSTYA 300
  301 IISGLLFLSF FQHQELRFLV PLVPLLVTNL NWTPLSSTLV NKKIFKGTWL LFNIIMAFIM 360
  361 GISHQAGIIQ FLGDYFHFRT EQMGVHIWWK TYSPPTWMYM SNNLTVSSLI NTQDGIESID 420
  421 EVAFSVGNHH VIDLKGCDLP LLTETIRRLR LNGSITPLTL VTPNSMTSEL KKLKRDGTIN 480
  481 LIPKRNYLFH LDLDHLDFND FTTFKPGLTV YSIELL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..516] Pfam 1000.0 Alg9-like mannosyltransferase family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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