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Protein Overview: LPX1

General Information:
Name(s) found: LPX1 / YOR084W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 387 amino acids

    Gene Ontology:
    Cellular Component: peroxisomal matrix [IDALink to PubMed article]
    Biological Process: peroxisome organization [IEPLink to PubMed article]
    Molecular Function: lipase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQNRFKKET KTCSASWPRA PQSTLCATDR LELTYDVYTS AERQRRSRTA TRLNLVFLHG  60
   61 SGMSKVVWEY YLPRLVAADA EGNYAIDKVL LIDQVNHGDS AVRNRGRLGT NFNWIDGARD 120
  121 VLKIATCELG SIDSHPALNV VIGHSMGGFQ ALACDVLQPN LFHLLILIEP VVITRKAIGA 180
  181 GRPGLPPDSP QIPENLYNSL RLKTCDHFAN ESEYVKYMRN GSFFTNAHSQ ILQNIIDFER 240
  241 TKASGDDEDG GPVRTKMEQA QNLLCYMNMQ TFAPFLISNV KFVRKRTIHI VGARSNWCPP 300
  301 QNQLFLQKTL QNYHLDVIPG GSHLVNVEAP DLVIERINHH IHEFVLTSPL QSSHIPQLTL 360
  361 EERAVMFDRA FDSFKNEALV KTTKQKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen IPL1 LPX1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data LPX1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..387] PSI-BLAST 53.39794 Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  1.08737094589901 bayes_pls_golite062009
  • catalytic activity
    		•  0.853693238072967 bayes_pls_golite062009
  • binding
    		•  0.401633301499824 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0490144635545247 bayes_pls_golite062009
  • protein binding
    		•  0.0473186402188429 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle