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Protein Overview: SRT1

General Information:
Name(s) found: SRT1 / YMR101C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 343 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed article]
    Biological Process: protein amino acid glycosylation [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: prenyltransferase activity [IDALink to PubMed article]
    dehydrodolichyl diphosphate synthase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMPSIIQIQ FVALKRLLVE TKEQMCFAVK SIFQRVFAWV MSLSLFSWFY VNLQNILIKA  60
   61 LRVGPVPEHV SFIMDGNRRY AKSRRLPVKK GHEAGGLTLL TLLYICKRLG VKCVSAYAFS 120
  121 IENFNRPKEE VDTLMNLFTV KLDEFAKRAK DYKDPLYGSK IRIVGDQSLL SPEMRKKIKK 180
  181 VEEITQDGDD FTLFICFPYT SRNDMLHTIR DSVEDHLENK SPRINIRKFT NKMYMGFHSN 240
  241 KCELLIRTSG HRRLSDYMLW QVHENATIEF SDTLWPNFSF FAMYLMILKW SFFSTIQKYN 300
  301 EKNHSLFEKI HESVPSIFKK KKTAMSLYNF PNPPISVSVT GDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..343] PSI-BLAST 324.512579 Undecaprenyl diphosphate synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • prenyltransferase activity
    		•  4.40397054534951 bayes_pls_golite062009
  • di-trans,poly-cis-decaprenylcistransferase activity
    		•  3.07573514495519 bayes_pls_golite062009
  • dehydrodolichyl diphosphate synthase activity
    		•  2.65131914933987 bayes_pls_golite062009
  • transferase activity
    		•  1.42376896518855 bayes_pls_golite062009
  • binding
    		•  1.19249144486008 bayes_pls_golite062009
  • catalytic activity
    		•  0.878978773660153 bayes_pls_golite062009
  • protein binding
    		•  0.555364167462951 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  0.256467886977999 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle