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Protein Overview: SUB1

General Information:
Name(s) found: SUB1 / YMR039C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Transcriptional coactivator, facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 292 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: termination of RNA polymerase II transcription [IGILink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IGILink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]
    Molecular Function: transcription coactivator activity [IGILink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYYNRYRNK RRSDNGGGNL SNSNNNNGGM PSGLSASDAI FDLGKNKRVT VRQFRNINLI  60
   61 DIREYYLDSS TGEMKPGKKG ISLTEDLYDE LLKHRLNIDE ALRRLGSKRP KTKMVRLLSD 120
  121 DEYEDDNNND STNNDKDKNG KDKNSPKKRR EDKSKASNES HDLEPRSKKK KPAPPTLLPH 180
  181 EENIQNAERE ANATLIIPGQ AGRKQQEERK QKEKEEAEEA KAKAVAEQEK EAKAKEKIAE 240
  241 PEPEPVPTLQ AKKEDIVSNI NESKDANSSD EEFAQSLEAE MNKAEDDISE EE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SUB1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] PSI-BLAST 116.917458 Transcriptional coactivator PC4 C-terminal domain
    2 View Details [117..292] MSA 4.048997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle