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Protein Overview: PLB2

General Information:
Name(s) found: PLB2 / YMR006C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 706 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed articleLink to PubMed article]
    extracellular region [IDALink to PubMed article]
    Biological Process: glycerophospholipid metabolic process [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: lysophospholipase activity [IDALink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLRNILQAS SLISGLSLAA DSSSTTGDGY APSIIPCPSD DTSLVRNASG LSTAETDWLK  60
   61 KRDAYTKEAL HSFLSRATSN FSDTSLLSTL FSSNSSNVPK IGIACSGGGY RAMLGGAGMI 120
  121 AAMDNRTDGA NEHGLGGLLQ SSTYLSGLSG GNWLTGTLAW NNWTSVQEIV DHMSESDSIW 180
  181 NITKSIVNPG GSNLTYTIER WESIVQEVQA KSDAGFNISL SDLWARALSY NFFPSLPDAG 240
  241 SALTWSSLRD VDVFKNGEMP LPITVADGRY PGTTVINLNA TLFEFTPFEM GSWDPSLNAF 300
  301 TDVKYLGTNV TNGKPVNKDQ CVSGYDNAGF VIATSASLFN EFSLEASTST YYKMINSFAN 360
  361 KYVNNLSQDD DDIAIYAANP FKDTEFVDRN YTSSIVDADD LFLVDGGEDG QNLPLVPLIK 420
  421 KERDLDVVFA LDISDNTDES WPSGVCMTNT YERQYSKQGK GMAFPYVPDV NTFLNLGLTN 480
  481 KPTFFGCDAK NLTDLEYIPP LVVYIPNTKH SFNGNQSTLK MNYNVTERLG MIRNGFEAAT 540
  541 MGNFTDDSNF LGCIGCAIIR RKQESLNATL PPECTKCFAD YCWNGTLSTS ANPELSGNST 600
  601 YQSGAIASAI SEATDGIPIT ALLGSSTSGN TTSNSTTSTS SNVTSNSNSS SNTTLNSNSS 660
  661 SSSISSSTAR SSSSTANKAN AAAISYANTN TLMSLLGAIT ALFGLI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..465] PSI-BLAST 173.228787 Domain from cytosolic phospholipase A2; Cytosolic phospholipase A2 catalytic domain
    2 View Details [466..706] deduced N/A No confident structure predictions are available.
    3 View Details [592..706] MSA 2.052996 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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