Protein Overview: YEH2

General Information:
Name(s) found:	YEH2 / YLR020C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74676452\|sp\|Q07950.1\|YEH2_YEAST RecName: Full=Sterol esterase 2; AltName: Full=Steryl ester hydrolase 2 [NCBI NR] gi\|6323048\|ref\|NP_013120.1\| Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism; Yeh2p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S64842 probable membrane protein YLR020c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1360324\|emb\|CAA97543.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Sterol esterase 2 OS=Saccharomyces cerevisiae GN=YEH2 PE=1 SV=1 [Swiss-Prot] YEH2 Membrane-anchored lipase required for steryl ester mobilization [mips] Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism [SGD] YLR020C, Chr XII from 181788-183404, reverse complement [yeast_orfs2] Chr XII from 181788-183404, reverse complement [yeastorf3.fasta] Chr XII from 183404-181788, reverse complement [yeastorf5.fasta] >Q07950 (Q07950) Chromosome XII reading frame ORF YLR020C [4932.FASTACCERV.txt] YLR020C SGDID:S0004010, Chr XII from 183404-181788, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] Yeh2p [Saccharomyces cerevisiae]gi\|1360324\|emb\|CAA97543.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132661\|pir\|\|S64842 probable membrane protein YLR020c - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas] (Q07950) S.cerevisiae chromosome XII reading frame ORF YLR020c [cerv4932.FASTAC] YEH2 SGDID:S000004010, Chr XII from 183404-181788, reverse complement, Verified ORF, "Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism; Yeh2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Sterol esterase 2 (Steryl ester hydrolase 2) [nr-271106-contam.fasta] [chemostatdb.fasta] Sterol esterase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YEH2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YEH2 SGDID:S000004010, Chr XII from 183405-181789, Genome Release 64-1-1, reverse complement, Verified ORF, "Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism" [yeast-030211-contam.fasta] YEH2 SGDID:S000004010, Chr XII from 183405-181789, Genome Release 64-2-1, reverse complement, Verified ORF, "Steryl ester hydrolase; catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism; YEH2 has a paralog, YEH1, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YLR020C SGDID:S000004010, Chr XII from 183405-181789, Genome Release 64-1-1, reverse complement, Verified ORF, "Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	538 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IDA] plasma membrane [IDA]
Biological Process:	cell wall mannoprotein biosynthetic process [IMP] sterol metabolic process [IMP ]
Molecular Function:	sterol esterase activity [IDA ][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNKVVDEVQ RLVSAIILTS FMTGLFILSL WKNYVTVHFQ HKNDPRDTRS SRTKIQPNDK  60
   61 KKKRPARHSR PLSISSTTPL DLQRDQENNI EYDRTVTSKL SMTSNASLSE NGDGNANIKM 120
  121 ETNVNQAPYA AENPFQNIAL AEDTKLVPDL KYYYKEYGID IEEFEVETDD GFIIDLWHFK 180
  181 SRLNDGVEEV KREPILLLHG LLQSCGAFAS SGRKSLAYFL YESGFDVWLG NNRCGLNAKW 240
  241 NMKKLGNDHS KKWDWDMHQM VQYDLKALIN YVLDSTGYAK LSLVAHSQGT TQGFMGLVNG 300
  301 EKLYASDFKL VDKLENFVAL APAVYPGPLL DEKAFVRLMA KGIDSPWYFG RRSFIPLMMT 360
  361 MRKLMVGTKI FSFLSYIMFN YLFDWNDVLW DRVLRDRNFL FSPVHISVKL MQWWLSPLPN 420
  421 KLSFKKGAEK IFPDKKTWFP IAKNDDDSGN NLDNNKLHLN PKRQNSEEFP HIIMFIPKQD 480
  481 RLVDGERLIN HFINHEANAV YKIWYIDEYS HLDVLWAHDV IDRIGKPMIE NLRFPNAR

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		TGL1 YEH1 YEH2

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	YEH2	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..121]	deduced	N/A	No confident structure predictions are available.
2	View Details	[122..538]	PSI-BLAST	296.758605	Gastric lipase

Protein Overview: YEH2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: