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Protein Overview: COX19

General Information:
Name(s) found: COX19 / YLL018C-A [SGD]
Description(s) found:
Found 22 descriptions.
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  • Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 98 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: metal ion transport [IDALink to PubMed article][ISSLink to PubMed article]
    respiratory chain complex IV assembly [IDALink to PubMed article][ISSLink to PubMed article]
    Molecular Function: copper ion binding [IDALink to PubMed article]
    metal ion transmembrane transporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGNPGSSLS ALRPTPPERG SFPLDHDGEC TKYMQEYLKC MQLVQNENAM NCRLLAKDYL  60
   61 RCRMDHQLMD YDEWSHLGLP EDAPGNNGKT IKDATDNK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ATP8 COX12 COX17 COX19 OLI1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COX19 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle