Protein Overview: PGU1

General Information:
Name(s) found:	PGU1 / YJR153W [SGD]
Description(s) found: Found 28 descriptions. SHOW ALL	Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins [SGD]
Organism:	Saccharomyces cerevisiae
Length:	361 amino acids
Gene Ontology:
Cellular Component:	extracellular region [IDA ]
Biological Process:	pectin catabolic process [IDA] pseudohyphal growth [NAS]
Molecular Function:	polygalacturonase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISANSLLIS TLCAFAIATP LSKRDSCTLT GSSLSSLSTV KKCSSIVIKD LTVPAGQTLD  60
   61 LTGLSSGTTV TFEGTTTFQY KEWSGPLISI SGSKISVVGA SGHTIDGQGA KWWDGLGDSG 120
  121 KVKPKFVKLA LTGTSKVTGL NIKNAPHQVF SINKCSDLTI SDITIDIRDG DSAGGHNTDG 180
  181 FDVGSSSNVL IQGCTVYNQD DCIAVNSGST IKFMNNYCYN GHGISVGSVG GRSDNTVNGF 240
  241 WAENNHVINS DNGLRIKTVE GATGTVTNVN FISNKISGIK SYGIVIEGDY LNSKTTGTAT 300
  301 GGVPISNLVM KDITGSVNST AKRVKILVKN ATNWQWSGVS ITGGSSYSGC SGIPSGSGAS 360
  361 C

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		CTS1 PGU1 SUC2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SST2	PGU1	1	Unpublished Fields Lab Data
View Screen	YPR091C	PGU1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..361]	PSI-BLAST	886.144602	Polygalacturonase

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
polygalacturonase activity	4.87547461518877	bayes_pls_golite062009
hydrolase activity	0.715715894047629	bayes_pls_golite062009
catalytic activity	0.67288476528593	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	0.1751072403659	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2