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Protein Overview: LSM8

General Information:
Name(s) found: LSM8 / YJR022W [SGD]
Description(s) found:
Found 14 descriptions.
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  • Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) that is part of spliceosomal U6 snRNP and is also implicated in processing of pre-tRNA, pre-snoRNA, and pre-rRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 128 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    U4/U6 x U5 tri-snRNP complex [IDALink to PubMed article][IPILink to PubMed article]
    U6 snRNP [IDALink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    Biological Process: nuclear mRNA splicing, via spliceosome [IPILink to PubMed article]
    Molecular Function: RNA binding [IDALink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQQAAYSTP YKKNTLSCTM SATLKDYLNK RVVIIKVDGE CLIASLNGFD KNTNLFITNV  60
   61 FNRISKEFIC KAQLLRGSEI ALVGLIDAEN DDSLAPIDEK KVPMLKDTKN KIENEHVIWE 120
  121 KVYESKTK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] PSI-BLAST 17.522879 B core SNRNP protein


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle