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Protein Overview: SEC28

General Information:
Name(s) found: SEC28 / YIL076W [SGD]
Description(s) found:
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  • ref|NP_012189.1| Part of a heptameric protein complex that regulates retrograde Golgi-to-ER protein traffic in eukaryotic cells; coatomer forms the COP I vesicle coat whose functions are essential; epsilon-COP coatomer subunit Sec28p [Saccharomyces cerevi [NCBI NR]
  • pir||S48368 probable membrane protein YIL076w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|556871|emb|CAA86094.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • SEC28 epsilon-COP coatomer subunit [mips]
  • Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth [SGD]
  • SEC28, Chr IX from 216466-217545 [yeast_orfs2]
  • Chr IX from 216466-217545 [yeastorf3.fasta]
  • SEC28 SGDID:S0001338, Chr IX from 216466-217545, Verified ORF [yeastflysequest.fasta]
  • Part of a heptameric protein complex that regulates retrograde Golgi-to-ER protein traffic in eukaryotic cells; coatomer forms the COP I vesicle coat whose functions are essential; epsilon-COP coatomer subunit Sec28p [Saccharomyces cerevisiae]gi|556871|e [nrdb_11152004_Chlamydomonas]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 359 amino acids

    Gene Ontology:
    Cellular Component: endosome [IDALink to PubMed article]
    COPI vesicle coat [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: vesicle coating [IGILink to PubMed article][IMPLink to PubMed article]
    ER to Golgi vesicle-mediated transport [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRLQWDKDI LFLIFKVILI FCWFFFSFLS SEKLQFLQKN TSSYSIRTDC EELGGEHRNR  60
   61 QKIMDYFNIK QNYYTGNFVQ CLQEIEKFSK VTDNTLLFYK AKTLLALGQY QSQDPTSKLG 120
  121 KVLDLYVQFL DTKNIEELEN LLKDKQNSPY ELYLLATAQA ILGDLDKSLE TCVEGIDNDE 180
  181 AEGTTELLLL AIEVALLNNN VSTASTIFDN YTNAIEDTVS GDNEMILNLA ESYIKFATNK 240
  241 ETATSNFYYY EELSQTFPTW KTQLGLLNLH LQQRNIAEAQ GIVELLLSDY YSVEQKENAV 300
  301 LYKPTFLANQ ITLALMQGLD TEDLTNQLVK LDHEHAFIKH HQEIDAKFDE LVRKYDTSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..212]
    [325..359]    		 ORFEUS 14.83 Neutrophil cytosolic factor 2 (NCF-2, p67-phox)
    3 View Details [213..260] ORFEUS 14.83 Neutrophil cytosolic factor 2 (NCF-2, p67-phox)
    4 View Details [261..324] ORFEUS 14.83 Neutrophil cytosolic factor 2 (NCF-2, p67-phox)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.07128880832802 bayes_pls_golite062009
  • protein binding
    		•  1.72061787550863 bayes_pls_golite062009
  • signal sequence binding
    		•  0.144756387712192 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle