Protein Overview: FIS1

General Information:
Name(s) found:	FIS1 / YIL065C [SGD]
Description(s) found: Found 29 descriptions. SHOW ALL	Protein involved in mitochondrial membrane fission and peroxisome abundance; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation [SGD]
Organism:	Saccharomyces cerevisiae
Length:	155 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial outer membrane [IDA ]
Biological Process:	response to drug [IMP] mitochondrial fission [IGI ][IMP ]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKVDFWPTL KDAYEPLYPQ QLEILRQQVV SEGGPTATIQ SRFNYAWGLI KSTDVNDERL  60
   61 GVKILTDIYK EAESRRRECL YYLTIGCYKL GEYSMAKRYV DTLFEHERNN KQVGALKSMV 120
  121 EDKIQKETLK GVVVAGGVLA GAVAVASFFL RNKRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PUS6	FIS1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	FIS1	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..155]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2