Protein Overview: TOM71

General Information:
Name(s) found:	TOM71 / YHR117W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731705\|sp\|P38825.1\|TOM71_YEAST RecName: Full=Protein TOM71; AltName: Full=71 kDa mitochondrial outer membrane protein [NCBI NR] gi\|6321909\|ref\|NP_011985.1\| Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; Tom71p [Sa [NCBI NR] pir\|\|S48959 mitochondrial outer membrane protein TOM71 - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|529136\|gb\|AAB68868.1\| Tom71p: 71-kDa component of the protein translocase of the outer membrane of mitochondria [Saccharomyces cerevisiae] [NCBI NR] gi\|1588674\|prf\|\|2209277A Tom72 protein [NCBI NR] TPR repeat-containing protein YHR117W OS=Saccharomyces cerevisiae GN=YHR117W PE=1 SV=1 [Swiss-Prot] Protein TOM71 OS=Saccharomyces cerevisiae GN=TOM71 PE=1 SV=1 [Swiss-Prot] TOM71 Protein translocase 71 kDa component of the outer membrane of mitochondria [mips] Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins [SGD] TOM71, Chr VIII from 342351-344270 [yeast_orfs2] Chr VIII from 342351-344270 [yeastorf3.fasta] (P38825) Hypothetical 71.9 kDa protein in ERP5-ORC6 intergenic region [4932.FASTACCERV.txt] TOM71 SGDID:S0001159, Chr VIII from 342351-344270, Verified ORF [yeastflysequest.fasta] Tom71p [Saccharomyces cerevisiae]gi\|731705\|sp\|P38825\|YHR7_YEAST Hypothetical 71.9 kDa protein in ERP5-ORC6 intergenic regiongi\|529136\|gb\|AAB68868.1\| Tom71p: 71-kDa component of the protein translocase of the outer membrane of mitochondria [Saccharomyce [nrdb_11152004_Chlamydomonas] TOM71 SGDID:S000001159, Chr VIII from 342352-344271, Verified ORF, "Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitoc [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Tom72 protein [nr-271106-contam.fasta] Tom71p: 71-kDa component of the protein translocase of the outer membrane of mitochondria [Saccharomyces cerevisiae] [nr-271106-contam.fasta] TPR repeat-containing protein YHR117W [nr-271106-contam.fasta] Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; Tom71p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] TOM71 SGDID:S000001159, Chr VIII from 342352-344271, Verified ORF, "Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Protein TOM71 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOM71 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] TOM71 SGDID:S000001159, Chr VIII from 342349-344268, Genome Release 64-1-1, Verified ORF, "Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins" [yeast-030211-contam.fasta] TOM71 SGDID:S000001159, Chr VIII from 342349-344268, Genome Release 64-2-1, Verified ORF, "Mitochondrial outer membrane protein; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; TOM71 has a paralog, TOM70, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YHR117W SGDID:S000001159, Chr VIII from 342349-344268, Genome Release 64-1-1, Verified ORF, "Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	639 amino acids
Gene Ontology:
Cellular Component:	integral to mitochondrial outer membrane [IDA] mitochondrion [IDA] mitochondrial outer membrane [IDA ]
Biological Process:	biological_process [IMP]
Molecular Function:	protein transporter activity [IPI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAENSLLRFI TKNKVAILAT VSAGTAAVGA YVYYQQIKQQ QQQQLKGTKD NRRQSEAFAG  60
   61 QNEDEADLKD DGSVVSGSNK RKKKKNKRKR NNKAKSGEGF DYPSLPNGEP DIAQLKGLSP 120
  121 SQRQAYAVQL KNRGNHFFTA KNFNEAIKYY QYAIELDPNE PVFYSNISAC YISTGDLEKV 180
  181 IEFTTKALEI KPDHSKALLR RASANESLGN FTDAMFDLSV LSLNGDFDGA SIEPMLERNL 240
  241 NKQAMKVLNE NLSKDEGRGS QVLPSNTSLA SFFGIFDSHL EVSSVNTSSN YDTAYALLSD 300
  301 ALQRLYSATD EGYLVANDLL TKSTDMYHSL LSANTVDDPL RENAALALCY TGIFHFLKNN 360
  361 LLDAQVLLQE SINLHPTPNS YIFLALTLAD KENSQEFFKF FQKAVDLNPE YPPTYYHRGQ 420
  421 MYFILQDYKN AKEDFQKAQS LNPENVYPYI QLACLLYKQG KFTESEAFFN ETKLKFPTLP 480
  481 EVPTFFAEIL TDRGDFDTAI KQYDIAKRLE EVQEKIHVGI GPLIGKATIL ARQSSQDPTQ 540
  541 LDEEKFNAAI KLLTKACELD PRSEQAKIGL AQLKLQMEKI DEAIELFEDS AILARTMDEK 600
  601 LQATTFAEAA KIQKRLRADP IISAKMELTL ARYRAKGML

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		SAM37 TOM20 TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOM71
View Details	Qiu et al. (2008)		TOM20 TOM22 TOM71

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MET18	TOM71	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	TOM71	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..121]	deduced	N/A	No confident structure predictions are available.
2	View Details	[122..187]	PSI-BLAST	114.594777	Protein phosphatase 5
3	View Details	[188..340]	ORFEUS	9.85	Protein farnesyltransferase alpha-subunit
4	View Details	[341..443]	PSI-BLAST	59.70927	Hop
5	View Details	[444..639]	MSA	6.298997	View MSA. Confident ab initio structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2