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Protein Overview: HTD2

General Information:
Name(s) found: HTD2 / YHR067W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: fatty acid biosynthetic process [IGILink to PubMed article][ISSLink to PubMed article]
    Molecular Function: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSKTWIFRD VLSSHRTKAF DSLLCRRLPV SKATKHLQLG EHFLFFPPSF EKLDRDGYFN  60
   61 YQNPASLLGN PDLRYRRRIW GQGELVQYLP VTLDQEYTCH ESIKYVKKIR DEHVVCIERT 120
  121 LLQERPENVS SPMDICLFER RVLMYTNSPA NKTAVKMPVG EENYKILKNF TVTDMDIVAY 180
  181 GQMSLNPHRI HWDKEYSRYV EGYDDIIMQG PFSVQLLQKC IQPFLEQPIR QLRYRNLNYI 240
  241 YPNTTLSICQ SLSSSSGMYT FQIRDLQKAN LVYMKADVFC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HTD2 SRB8 SSN2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data HTD2 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..280] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle