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Protein Overview: RRP3

General Information:
Name(s) found: RRP3 / YHR065C [SGD]
Description(s) found:
Found 10 descriptions.
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  • Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 543 amino acids

    Gene Ontology:
    Cellular Component: nuclear outer membrane [TASLink to PubMed article]
    nucleolus [TASLink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: ATP-dependent RNA helicase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNLKLINEH LAIVHGIHRI VTYLRSNIYQ DSVKYFTESA IKMSKIVKRK EKKANDELTS  60
   61 LAEKIRAKAL ENQKKLIEAE KEGGSESDSE EDATAEKKKV LKSKSKSTVS TQNENTNEDE 120
  121 SFESFSELNL VPELIQACKN LNYSKPTPIQ SKAIPPALEG HDIIGLAQTG SGKTAAFAIP 180
  181 ILNRLWHDQE PYYACILAPT RELAQQIKET FDSLGSLMGV RSTCIVGGMN MMDQARDLMR 240
  241 KPHIIIATPG RLMDHLENTK GFSLRKLKFL VMDEADRLLD MEFGPVLDRI LKIIPTQERT 300
  301 TYLFSATMTS KIDKLQRASL TNPVKCAVSN KYQTVDTLVQ TLMVVPGGLK NTYLIYLLNE 360
  361 FIGKTMIIFT RTKANAERLS GLCNLLEFSA TALHGDLNQN QRMGSLDLFK AGKRSILVAT 420
  421 DVAARGLDIP SVDIVVNYDI PVDSKSYIHR VGRTARAGRS GKSISLVSQY DLELILRIEE 480
  481 VLGKKLPKES VDKNIILTLR DSVDKANGEV VMEMNRRNKE KIARGKGRRG RMMTRENMDM 540
  541 GER

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..333] PSI-BLAST 619.457575 Putative DEAD box RNA helicase
    3 View Details [334..543] PSI-BLAST 619.457575 Putative DEAD box RNA helicase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle