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Protein Overview: RNH70

General Information:
Name(s) found: RNH70 / YGR276C [SGD]
Description(s) found:
Found 28 descriptions.
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  • 3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 553 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: RNA processing [IMPLink to PubMed article]
    Molecular Function: 3'-5' exonuclease activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVEGPDTNF VSDLALGSKK RRLSKTSVQE DDHTNVVSEV NKNKKKKKAK PMTCTLLKSV  60
   61 VEKGIGIKDV RDMTQYLLQA ENNSPKWIDI CNRSSLQKMI VLFIPGLQPD DFENGKNTFN 120
  121 EISDDNFKYI PGEIASTFHT FPVMAPGSKM TLFSPYNSFI NVGLSKMEKI NKLKELQKKK 180
  181 KITINDLVLS EQQLVANDYP LDSGDTNFDT DWVQTVDFTH GGSHIFALDC EMCLSEQGLV 240
  241 LTRISLVNFD NEVIYEELVK PDVPIVDYLT RYSGITEEKL TVGAKKTLRE VQKDLLKIIS 300
  301 RSDILIGHSL QNDLKVMKLK HPLVVDTAII YHHKAGDPFK PSLKYLSETF LNKSIQNGEH 360
  361 DSVEDARACL ELTKLKILNG LAFGIGINTE NLFTKLHRFE VKTVLLNDMI IKNHTEDDSK 420
  421 GQLIRCVEDD ETWTHIHENL NKDVKLIVGR IKNLERSRNY NKKPRKETPS FDASMVLHDI 480
  481 GQHLTQLYEN ATPGTMILIM SGTGDTRPWN NLSTELEFIQ DKKERLDKRR EREPEIVEAI 540
  541 KLARGGVASF TVK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..163] MSA 1.047985 View MSA. No confident structure predictions are available.
    2 View Details [164..462] PSI-BLAST 10.30103 STRUCTURE OF LARGE FRAGMENT OF ESCHERICHIA COLI DNA POLYMERASE I COMPLEXED WITH D/TMP
    3 View Details [463..553] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle