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Protein Overview: SLI1

General Information:
Name(s) found: SLI1 / YGR212W [SGD]
Description(s) found:
Found 27 descriptions.
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  • N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: response to drug [IDALink to PubMed article]
    Molecular Function: N-acetyltransferase activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLKLSAIES YFFHRSRLNL HSCFYVGIKL NELPKKSQLI AALKYTVIQH ERLTCNVFYD  60
   61 ELKKENFLQN ILEPLKFCDL VEYRHDWDQL GETEINHIFQ RYNFSYNENK PLWKILILPN 120
  121 QNQMLLLTDH VLMDGMSAIH VWETFMEGLQ MQQPVEIDET IYSPSLNSST EKIMSAPLYG 180
  181 DWPIPWNWHI VRQLVSRLHY WFPQTVVKNN RNLIQFANYS FPKDLLDDKP SDGTQKYKVK 240
  241 NTNHQWEFRL SPTHLNDILQ ECKANNTSLT SLLGALVCTS FEKIAAHEYT GSFLKIELPM 300
  301 NIRKPFERVL KLPSDDKLAV GNFIAVIEFN HKLHQNRGIW DIASQIQRAI RSSSEDKIID 360
  361 KVNEVKLLEV ISSQQYIEDK ISLNNGPSST FEVTNLGFQT FKDACNTSLP FYIVDATFNE 420
  421 PQGISSIFSL SVISTPGNGL HCCISYPNTL TKVLEPHWQY MKDYLNLY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239] MSA 1.006942 View MSA. No confident structure predictions are available.
    2 View Details [240..468] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.932834665975468 bayes_pls_golite062009
  • catalytic activity
    		•  0.639338887128759 bayes_pls_golite062009
  • transferase activity
    		•  0.327835782883585 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle