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Protein Overview: CAX4

General Information:
Name(s) found: CAX4 / YGR036C [SGD]
Description(s) found:
Found 33 descriptions.
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  • Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 239 amino acids

    Gene Ontology:
    Cellular Component: integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    Biological Process: lipid biosynthetic process [IGILink to PubMed article][IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    Molecular Function: pyrophosphatase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSTAAAINP NPNVIPFDDT YILYDSHDFL SFLSAYFSLM PILVLAFYLS WFIITRELEA  60
   61 CIVAFGQLMN EIFNNVIKNI IKQPRPVSFG ASFQNDTIRS GYGMPSAHSQ FMGFCFTYNS 120
  121 LKIYTSWKNL NFLEKCIFSG ALALLSFCVC FSRVYLHYHN LDQVIVGFSV GALTGSLYFF 180
  181 IVGIIRELGL INWFLKLRIV RLFYMTDSYN LAPLTLKENY EAYWKRINQR SFNDKSKRD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CAX4 GAA1 PMR1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CAX4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239] PSI-BLAST 14.0 Bacterial acid phosphatase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.767627914425245 bayes_pls_golite062009
  • phosphatase activity
    		•  0.722810330266611 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.534563060036778 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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