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Protein Overview: FCY22

General Information:
Name(s) found: FCY22 / YER060W-A [SGD]
Description(s) found:
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  • gi|74583809|sp|Q12119.1|FCY22_YEAST RecName: Full=Purine-cytosine permease FCY22; Short=PCP FCY22; AltName: Full=Cytosine/purine transport protein FCY22; AltName: Full=Fluorocytosine resistance protein 22 [NCBI NR]
  • gi|6320903|ref|NP_010982.1| Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function; Fcy22p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1381130|gb|AAB64610.1| Fcy22p: Puring-cytosine permase [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1321944|emb|CAA66033.1| FCYX [Saccharomyces cerevisiae] [NCBI NR]
  • Purine-cytosine permease FCY22 OS=Saccharomyces cerevisiae GN=FCY22 PE=1 SV=1 [Swiss-Prot]
  • FCY22 Putative purine/cytosine permease [mips]
  • Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function [SGD]
  • FCY22, Chr V from 276570-278162 [yeast_orfs2]
  • Chr V from 276570-278162 [yeastorf3.fasta]
  • >Q12119 (Q12119) Putative ribosomal protein FCYX [4932.FASTACCERV.txt]
  • FCY22 SGDID:S0002958, Chr V from 276570-278162, Verified ORF [yeastflysequest.fasta]
  • Fcy22p [Saccharomyces cerevisiae]gi|1321944|emb|CAA66033.1| FCYX [Saccharomyces cerevisiae]gi|1381130|gb|AAB64610.1| Fcy22p: Puring-cytosine permase [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas]
  • (Q12119) FCYX protein [cerv4932.FASTAC]
  • FCY22 SGDID:S000002958, Chr V from 276570-278162, Verified ORF, "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Fcy22p: Puring-cytosine permase [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • FCYX [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Purine-cytosine permease FCY22 (PCP FCY22) (Cytosine/purine transport protein FCY22) (Fluorocytosine resistance protein 22) [nr-271106-contam.fasta]
  • Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function; Fcy22p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Purine-cytosine permease FCY22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FCY22 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • FCY22 SGDID:S000002958, Chr V from 276572-278164, Genome Release 64-1-1, Verified ORF, "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" [yeast-030211-contam.fasta]
  • FCY22 SGDID:S000002958, Chr V from 276572-278164, Genome Release 64-2-1, Verified ORF, "Putative purine-cytosine permease; very similar to Fcy2p but cannot substitute for its function" [20141208_orf_trans.fasta]
  • YER060W-A SGDID:S000002958, Chr V from 276572-278164, Genome Release 64-1-1, Verified ORF, "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • Purine-cytosine permease FCY22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FCY22 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 530 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    Biological Process: biological_process [ND]
    AMP metabolic process [ISSLink to PubMed article]
    Molecular Function: nucleobase transmembrane transporter activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEKLAMSMV DIKDAGSELR DLESGALDTK SSAADVYYEG VELHRTNEFI DNKPSFFNRI  60
   61 AAALNAETKG IEPVTEDEKN DDSILNAATI WFSANMVIVA YSVGALGPLV FGLNFGQSVL 120
  121 VIIFFNILGL IPVALFSLFG VELGLRQMIL SRYLAGNITA RFFSLVNVIA CVGWCVLNIS 180
  181 VSAQLLNMVN EGSGHNCPIW AGCLIIAGGT VLVTFFGYSV VHAYEKWSWV PNFAAFLVII 240
  241 AQLSRSGKFK GGEWVGGATT AGGVLSFGSS VFGSAAGWAT YAADYTVYMP KTTSKYKIFF 300
  301 SVVAGLAFPL FFTMILGAAC GMAALNDPTW KSYYDKNAMG GVIYAILVPN SLNGFGQFCC 360
  361 VLLALSTVAN NVPGMYTVAL SAQALWAPLA KIPRVVWTMA GNAATLGISI PATYYFDGFM 420
  421 ENFMDSIGYY LAIYIAIACS EHFIYRRSFS AYNIDDWDNW EHLPIGIAGT AALIAGAFGV 480
  481 ALGMCQTYWV GEISRLIGEY GGDIGFELGG SWAFIIYNIV RPLELKYFGR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [70..530] Pfam 156.017729 Permease for cytosine/purines, uracil, thiamine, allantoin No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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