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Protein Overview: MEI4

General Information:
Name(s) found: MEI4 / YER044C-A [SGD]
Description(s) found:
Found 25 descriptions.
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  • Meiosis-specific protein involved in double-strand break formation during meiotic recombination; required for chromosome synapsis and production of viable spores [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 408 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: ascospore formation [TASLink to PubMed article]
    reciprocal meiotic recombination [TASLink to PubMed article]
    meiotic DNA double-strand break formation [TASLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRGKLEDME QKETSEVDWI ICFALIQSRN PTLWKRALSR KKGDVEDVGA LKSEKNLKIN  60
   61 PRENSKHIYK WVAPFENGFL NNKSLFAHLE PIYNFLCQNK YKSFEDAVGL KELQSFSKDV 120
  121 STADINNWFL PRYKILLKIL SLKTKEIDFR GLSQVFQTLQ ILLVSHYSHR IDSDSSFKRT 180
  181 LIDVHVFNFI AKFLFNRILL KKNQNDPKWL QNFYDQGDGK HLCDKVDYKR LCSLHFTLIY 240
  241 SIINIQLIKI KTNQTFEPQI LKYVSVLKLI EHILIIIESL IHVLIRFVSK HKLICINRKK 300
  301 AYCRVYLERE LSLKKTYLKN FYSVISGVPE KELGGLLKIL KIVILSLLET FESIEWQHLK 360
  361 PFLEKFPAHE ISLQKKRKYI QAALLITAER NLIARFRLSR WFNETENI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..408] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle