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Protein Overview: RRP8

General Information:
Name(s) found: RRP8 / YDR083W [SGD]
Description(s) found:
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  • gi|731366|sp|P38961|YD083_YEAST Hypothetical 47.2 kDa protein in STN1-AFR1 intergenic region [NCBI NR]
  • pir||S48770 probable membrane protein YDR083w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|558254|emb|CAA57610.1| 2 putative transmembrane spans [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1431555|emb|CAA98903.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • (P38961) Hypothetical 47.2 kDa protein in STN1-AFR1 intergenic region [Swiss-Prot]
  • RRP8 - protein involved in cleavage at site A2 in pre-rRNA in the pathway of ribosomal RNA processing [mips]
  • Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation [SGD]
  • RRP8, Chr IV from 612010-613218 [yeast_orfs2]
  • Chr IV from 612010-613218 [yeastorf3.fasta]
  • 2 putative transmembrane spans [Saccharomyces cerevisiae]gi|1431555|emb|CAA98903.1| unnamed protein product [Saccharomyces cerevisiae]gi|629934|pir||S48770 probable membrane protein YDR083w - yeast (Saccharomyces cerevisiae)gi|731366|sp|P38961|YD61_YEA [nrdb_11152004_Chlamydomonas]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Hypothetical 47.2 kDa protein in STN1-AFR1 intergenic region [nr-271106-contam.fasta]
  • 2 putative transmembrane spans [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 402 amino acids

    Gene Ontology:
    Cellular Component: nucleolus [IDALink to PubMed article]
    Biological Process: telomere maintenance [IMPLink to PubMed articleLink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    rRNA processing [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: methyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHILYIYYIK QIRTLTKFYM ALFNVEGWSI KTKTVAFDNK TNKSSKDKKK NNRKNGKLTR  60
   61 EQKLKEETEA ELKEQVEDIP SEGSVAKDIP KKNQEKSDQN ETSKKRKHDE EAPLMQVKEN 120
  121 IEKPTKKQLT PLQQKMMAKL TGSRFRWINE QLYTISSDEA LKLIKEQPQL FDEYHDGFRS 180
  181 QVQAWPENPV DVFVDQIRYR CMKPVNAPGG LPGLKDSKEI VIADMGCGEA QLALEINNFF 240
  241 KNYNKKAKKY LKRRHKVHSF DLKKANERIT VADIRNVPLP DESCTIVVFC LALMGTNFLD 300
  301 FIKEAYRILA PRGELWIAEI KSRFSDGKGN EFVDALKLMG FFHKKTFDEN KMFTRFEFFK 360
  361 PPAEIIEERR QKLERRQKFI EVETEKEELE KKRRKIAEEN GS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] deduced N/A No confident structure predictions are available.
    2 View Details [128..191]
    [324..402]    		 PSI-BLAST 13.39794 No description for 1ic3A_ was found.
    3 View Details [192..323] PSI-BLAST 13.39794 No description for 1ic3A_ was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle