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Protein Overview: ALG7

General Information:
Name(s) found: ALG7 / YBR243C [SGD]
Description(s) found:
Found 34 descriptions.
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  • UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 448 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [ICLink to PubMed article]
    Biological Process: protein amino acid N-linked glycosylation [TASLink to PubMed article]
    Molecular Function: UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLFSLALI TCLIYYSKNQ GPSALVAAVG FGIAGYLATD MLIPRVGKSF IKIGLFGKDL  60
   61 SKPGRPVLPE TIGAIPAAVY LFVMFIYIPF IFYKYMVITT SGGGHRDVSV VEDNGMNSNI 120
  121 FPHDKLSEYL SAILCLESTV LLGIADDLFD LRWRHKFFLP AIAAIPLLMV YYVDFGVTHV 180
  181 LIPGFMERWL KKTSVDLGLW YYVYMASMAI FCPNSINILA GVNGLEVGQC IVLAILALLN 240
  241 DLLYFSMGPL ATRDSHRFSA VLIIPFLGVS LALWKWNRWP ATVFVGDTYC YFAGMVFAVV 300
  301 GILGHFSKTM LLLFIPQIVN FIYSCPQLFK LVPCPRHRLP KFNEKDGLMY PSRANLKEEP 360
  361 PKSIFKPILK LLYCLHLIDL EFDENNEIIS TSNMTLINLT LVWFGPMRED KLCNTILKLQ 420
  421 FCIGILALLG RHAIGAIIFG HDNLWTVR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115] deduced N/A No confident structure predictions are available.
    2 View Details [116..339] Pfam 84.356547 Glycosyl transferase family 4 No confident structure predictions are available.
    3 View Details [340..448] MSA 1.106979 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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