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Protein Overview: TSC3

General Information:
Name(s) found: TSC3 / YBR058C-A [SGD]
Description(s) found:
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  • gi|85541969|sp|Q3E790.1|TSC3_YEAST RecName: Full=Serine palmitoyltransferase-regulating protein TSC3; AltName: Full=Temperature-sensitive CSG2-mutant suppressor protein 3 [NCBI NR]
  • gi|7493849|pir||S78706 protein YBR058c-a - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|14270689|ref|NP_116327.1| Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis; Tsc3p [Saccharomyces cerevisiae] [NCBI NR]
  • Serine palmitoyltransferase-regulating protein TSC3 OS=Saccharomyces cerevisiae GN=TSC3 PE=1 SV=1 [Swiss-Prot]
  • TSC3 Protein required for optimal serine palmitoyltransferase activity [mips]
  • Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis [SGD]
  • TSC3, Chr II from 356283-356525, reverse complement [yeast_orfs2]
  • Chr II from 356283-356525, reverse complement [yeastorf3.fasta]
  • Chr II from 356525-356283, reverse complement [yeastorf5.fasta]
  • TSC3 SGDID:S0007521, Chr II from 356526-356284, reverse complement, Verified ORF [yeastflysequest.fasta]
  • TSC3 SGDID:S0007521, Chr II from 356564-356322, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis [Saccharomyces cerevisiae]gi|7493849|pir||S78706 protein YBR058c-a - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas]
  • TSC3 SGDID:S000007521, Chr II from 356564-356322, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Serine palmitoyltransferase-regulating protein TSC3 (Temperature-sensitive CSG2-mutant suppressor protein 3) [nr-271106-contam.fasta]
  • protein YBR058c-a - yeast (Saccharomyces cerevisiae) [nr-271106-contam.fasta]
  • Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis; Tsc3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Serine palmitoyltransferase-regulating protein TSC3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • TSC3 SGDID:S000007521, Chr II from 356566-356324, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis" [yeast-030211-contam.fasta]
  • TSC3 SGDID:S000007521, Chr II from 356566-356324, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase; involved in sphingolipid biosynthesis; Lcb1p and Lcb2p are the two components of serine palmitoyltransferase" [20141208_orf_trans.fasta]
  • YBR058C-A SGDID:S000007521, Chr II from 356566-356324, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 80 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    microsome [IDALink to PubMed article]
    Biological Process: 3-keto-sphinganine metabolic process [IPILink to PubMed article]
    sphingolipid biosynthetic process [TASLink to PubMed article]
    Molecular Function: enzyme activator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQHKSSMVY IPTTKEAKRR NGKSEGILNT IEEVVEKLYW TYYIHLPFYL MASFDSFFLH  60
   61 VFFLTIFSLS FFGILKYCFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TSC3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle