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Protein Overview: BUD14

General Information:
Name(s) found: BUD14 / YAR014C [SGD]
Description(s) found:
Found 9 descriptions.
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  • Protein involved in bud-site selection, Bud14p-Glc7p complex is a cortical regulator of dynein; inhibitor of the actin assembly factor Bnr1p (formin); diploid mutants display a random budding pattern instead of the wild-type bipolar pattern [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 702 amino acids

    Gene Ontology:
    Cellular Component: incipient cellular bud site [IDALink to PubMed article]
    cellular bud tip [IDALink to PubMed article]
    cellular bud neck [IDALink to PubMed article]
    Biological Process: cytoskeleton organization [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    cell morphogenesis during vegetative growth [IGILink to PubMed article]
    regulation of transcription, DNA-dependent [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein phosphatase type 1 regulator activity [IDALink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKEEHVDE TSASGVKEVS SIAARHDNGY APSLITSTSG MDSFQSHALL NDPTLIEDYS  60
   61 DIINNRPTSG SKLTLGNEDS ESMGGSVVVT PTSNKSSPFN SKLNILSNAA EKGHDVLRNR 120
  121 DDDKELEEEN VEKHMHSNSK RDQRHYKENS SELPDSYDYS DSEFEDNLER RLQEIETDSV 180
  181 DSADKDEVHF SVNNTMNPDV DDFSDGLKYA ISEDEDEEEN YSDDDDFDRK FQDSGFQGEK 240
  241 DDLEEENDDY QPLSPPRELD PDKLYALYAF NGHDSSHCQL GQDEPCILLN DQDAYWWLVK 300
  301 RITDGKIGFA PAEILETFPE RLARLNCWKN ENMSSQSVAS SDSKDDSISS GNKNQSDAES 360
  361 IIPTPALNGY GKGNKSVSFN DVVGYADRFI DDAIEDTSLD SNDDGGEGNG QSYDDDVDND 420
  421 KETKVTHRDE YTEAKLNFAK FQDDDTSDVV SDVSFSTSLN TPLNVKKVRR QDNKNESEPK 480
  481 TSSSKDREDD YNANRYVGQE KSEPVDSDYD TDLKKVFEAP RMPFANGMAK SDSQNSLSTI 540
  541 GEFSPSSSEW TNESPSTPIV EESSSIPSSR AIRTFTYIMQ NRKLRDNKRG KHRGQIQASL 600
  601 GSSGGMPNQT DAEQPKEELE KHHSTPEEEK QSTLSLHSSS EEDFYMDEQR AVSSASINSS 660
  661 LSGSRALSNT NMSDPASKPN SLVQHLYAPV FDRMDVLMKP IG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] MSA 1.003935 View MSA. No confident structure predictions are available.
    2 View Details [157..253] deduced N/A No confident structure predictions are available.
    3 View Details [254..338] PSI-BLAST 3.0 Fyn proto-oncogene tyrosine kinase, SH3 domain; Tyrosine kinase Fyn
    4 View Details [339..702] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle