YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PMT2

General Information:
Name(s) found: PMT2 / YAL023C [SGD]
Description(s) found:
Found 6 descriptions.
SHOW ALL
  • Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 758 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [TASLink to PubMed article]
    Biological Process: protein amino acid O-linked glycosylation [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: dolichyl-phosphate-mannose-protein mannosyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSSTGYS KNNAAHIKQE NTLRQRESSS ISVSEELSSA DERDAEDFSK EKPAAQSSLL  60
   61 RLESVVMPVI FTALALFTRM YKIGINNHVV WDEAHFGKFG SYYLRHEFYH DVHPPLGKML 120
  121 VGLSGYLAGY NGSWDFLLEI YPDYLDYVKM RLFNASFSAL CVPLAYFTAK AIGFSLPTVW 180
  181 LMTVLVLFEN SYSTLGRFIL LDSMLLFFTV ASFFSFVMFH NQRSKPFSRK WWKWLLITGI 240
  241 SLGCTISVKM VGLFIITMVG IYTVIDLWTF LADKSMSWKT YINHWLARIF GLIIVPFCIF 300
  301 LLCFKIHFDL LSHSGTGDAN MPSLFQARLV GSDVGQGPRD IALGSSVVSI KNQALGGSLL 360
  361 HSHIQTYPDG SNQQQVTCYG YKDANNEWFF NRERGLPSWS ENETDIEYLK PGTSYRLVHK 420
  421 STGRNLHTHP VAAPVSKTQW EVSGYGDNVV GDNKDNWVIE IMDQRGDEDP EKLHTLTTSF 480
  481 RIKNLEMGCY LAQTGNSLPE WGFRQQEVVC MKNPFKRDKR TWWNIETHEN ERLPPRPEDF 540
  541 QYPKTNFLKD FIHLNLAMMA TNNALVPDPD KFDYLASSAW QWPTLNVGLR LCGWGDDNPK 600
  601 YFLLGTPAST WASSVAVLAF MATVVILLIR WQRQYVDLRN PSNWNVFLMG GFYPLLAWGL 660
  661 HYMPFVIMSR VTYVHHYLPA LYFALIILAY CFDAGLQKWS RSKCGRIMRF VLYAGFMALV 720
  721 IGCFWYFSPI SFGMEGPSSN FRYLNWFSTW DIADKQEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..334] Pfam 104.79588 Dolichyl-phosphate-mannose-protein mannosyltransferase No confident structure predictions are available.
    2 View Details [335..399] Pfam 13.721246 MIR domain No confident structure predictions are available.
    3 View Details [400..466] Pfam 15.337242 MIR domain No confident structure predictions are available.
    4 View Details [467..543] Pfam 18.229148 MIR domain No confident structure predictions are available.
    5 View Details [544..758] MSA 4.033963 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle