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Protein Overview: tlh2

General Information:
Name(s) found: tlh2 / SPBCPT2R1.08c [Sanger Pombe]
Description(s) found:
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  • gi|92790385|emb|CAJ90629.1| SPBCPT2R1.08c [Schizosaccharomyces pombe] [NCBI NR]
  • gi|162312347|ref|XP_001713158.1| RecQ type DNA helicase Tlh1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|157310482|emb|CAO77679.1| RecQ type DNA helicase Tlh1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|146336810|sp|Q1RKN3.1|TLH2_SCHPO RecName: Full=ATP-dependent DNA helicase tlh2; AltName: Full=Sub-telomeric helicase RecQ homolog 2 [NCBI NR]
  • RecQ type DNA helicase Tlh1 [Sanger Pombe]
  • ATP-dependent DNA helicase tlh2 OS=Schizosaccharomyces pombe GN=tlh2 PE=2 SV=1 [Swiss-Prot]
  • |tlh2||RecQ type DNA helicase Tlh1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBCPT2R1.08c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • ATP-dependent DNA helicase tlh2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tlh2 PE=2 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 1919 amino acids

    Gene Ontology:
    Cellular Component: chromosome, telomeric region [IDALink to PubMed article]
    nucleus [NASLink to PubMed article]
    Biological Process: telomere maintenance via recombination [IEPLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    zinc ion binding [IEA]
    ATP-dependent 3'-5' DNA helicase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVASEIAKV ASKTARDIAG CFTCQCGTQF DNVERIVQHF KECRYRDETC KDDDIVVYEP  60
   61 SSFVQDEKKD KPIIVEAASE ATSEEACNSS KERQLPALSA LSALSTLTTS ANDDLWTARL 120
  121 IWQSTNDTKL DNSPSSNYTD LNHKLANYGL SILSIHALMC VECECLLNVI HTAQHMQIVH 180
  181 KLELNEDLLW FQELRTLKLK SPTNVLQTHS SQTHVYPYIR GLPVLLNGYE CVPCTKNGTG 240
  241 FVHAIMDTFR HHVRRTHGKV IKLENCIRRT ALQTVKNKYA QRCQFFKVDY VPLNGGEEEE 300
  301 EEEGEEKEDA QNIKERMVDF CFSKFMEKNQ QRREQQDKGE NKKRQDDVDQ ATDNNTNTIL 360
  361 EDDEKDNDEE EEEEIVNARE KNLLNQQFNW TAIVKKLGEN WDQLVRFEYT NGIVTLDTIV 420
  421 NQLIRYYYRG FRHLSGMTMG MRRMFTQGGS YSAQERGLCR LEQKDTVVRY AQSAALYLIF 480
  481 LLRRPSADSG IRRHLEAMCG ATVERKEGGS NSSSNISNVA NFDSAEDDND NDNDNDRDSN 540
  541 NNNNNNNTNT DDDDKLAYLE LHEALKLAFL QQYDFSKNVQ DLEIMEFLAC MSLHKDGTSK 600
  601 YAYEISACFA PLIYTCRLVA ACELQRLIDE KQIDLLSIPS FQTAGSIAYA HVFCFITLGQ 660
  661 RNLYDVLYET QKVVRDIIRT EGYANTLQGL SPSTVLFQPR SNSMYPCIGD AFNNMVRLDL 720
  721 SELTALYEGM FAKVQDLLKE LCFDMNVEKL LPISLLRSIG DDINNSKLGY SFFKESIEIR 780
  781 SSHSVLLRTI LKNSELCHRF FPSMSKKDLT KLFGGVSDQQ RNECDNYSNH YNDNSNDNDN 840
  841 DVFLKLHWSK SAIKKYETKA SIFNELLFCL VYISAGQPAR AQEMVYWTLR NGKYKTRELY 900
  901 LMFGRLMIYS RYDKTRNMKF AEKPIPRFLS EPLSILALRY YVLVRPLEAL MKYVTTADRS 960
  961 KVAVYLDFMF VIAGERLQRD LPYRIFPKAT YQCIQKPLGF RNYRHIAHYF KEKNIEEEMT1020
 1021 RESYFDLQAG HTRNTALYIY GRTMDNLHYL PSDYFANFFR ASYKWQELLQ IRDNPTHGLL1080
 1081 VETKHPFIKR VDQLEEALNE KLARLVGEQM VEGDKEKDKT NEEKNKDEVK AEMTQPVVNQ1140
 1141 DSHDLQDQLA TTPTAPTAFH YRPGLLQPSQ TSVQHCCWAL SQYYGLEAKF RSLKQFQSVY1200
 1201 FSLLNRMNLI TVLPTGGGKS LSFLIPALIE KKRQTPGKVM NMVTLVLVPM MSLRQDMMLR1260
 1261 VNEKGLLVCS GNWTAFKDVR LTLETQLPDL FILTYESALT NSGLRFFESL ATLGRLARVV1320
 1321 IDEAHLLLTS GAWRTALSRA SRLSGLYAPL HLLSATFPRQ LEMVARQTFC TNFYVLRETS1380
 1381 TARENIFYFL HPYDNTEFLL DLRTLMKRTK VFEGDGRAII FCRTKKDVEY IHRRLHQSDL1440
 1441 FAHTHVTIYT GDVSDEERQM NFDAFRNANG KTRIMIATKA FGLGINYMGV RLVVHYGLPA1500
 1501 SSMDYVQETG RAGRDGKYAI AALFYEKYDS TWSSYVEDSM KNFLNDNTMC VRSFLASEMD1560
 1561 GECVCCASFA NCVYCSRCSD SLLGEESTVS TMYGVKPTLP ETPKPAIATH SRYNASFSSS1620
 1621 PPPQPGNSSG MSAMNTNTTS TTPVSLSELS EITLFPSSVS PTWKKSFGNA NTNLKYGLED1680
 1681 MSLSHRRGHK RTYDEHLNNV QQGVNHDMNR VHGSVGGMSG IVGIGIGIGD GDGDGDVDSR1740
 1741 TIHFAEYKSR VQAVKKQWVD STDISAQLER FFRVYKDECL SCTLGNPDTE IRAHTGKACP1800
 1801 VRLSTCYKCG KADHNLRECK LRIRFQGLCL FCGLTKFEHA DSDMAYTSDC RSWARKANLI1860
 1861 SLVYYAWNNV QYRRTIADKF LQGDVRDQAF YGFVCCSTTT NSAFVLVIHY LLSDVLQIM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.49

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle