Protein Overview: tefu-PB

General Information:
Name(s) found:	tefu-PB / FBpp0110174 [FlyBase]
Description(s) found: Found 19 descriptions. SHOW ALL	The gene telomere fusion is referred to in FlyBase by the symbol Dmel\tefu (CG6535, FBgn0045035). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11057922..11067884. It has the cytological map location 88E3-88E4. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: G2/M transition DNA damage checkpoint; telomere maintenance; chromosome organization; chromatin silencing at telomere; telomere capping. 23 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; dorsal mesothoracic disc; chromosome, telomeric region; interommatidial bristle; macrochaeta; condensed chromosome; wing; ommatidium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	2767 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	cell cycle checkpoint [ISS] chromosome organization [IMP] telomere maintenance [IMP] G2/M transition DNA damage checkpoint [IMP] phosphorylation [NAS] telomere capping [IMP] chromatin silencing at telomere [IMP]
Molecular Function:	protein kinase activity [ISS][NAS] phosphotransferase activity, alcohol group as acceptor [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSALLNEIQR ILGDLQSGKA ASRNKGIQQL DEKLSSCRED LDKLFLSKTS DISWTTIFEA  60
   61 SKEALFKQAG NLEDVNEKVF KTLAGKNYLY DNVLEKITQF NLEAGSQTSG NGHFLAKTSI 120
  121 FSAFEDGIKM RVVVKYFGDR ILSLLEKGIY SSVSYVRDLK INEYSRILSY LFELNVDMDE 180
  181 VLRTRILKCI TRTVSLAKDR VQLHVDLVEY LPELSSFALS AFGARKTEIV RVYLIFASEL 240
  241 AVNYNHQLNV HMQEILPKLC EYHDEDAFRD DTRNLFFQCV SKSLHSMYLK MDMCDFNTLG 300
  301 VPVHEKWPQT LLRLKTIVNV EIRKNSWARC KNALLSNNKF SDPFIKMSAL AMYIVLWHLE 360
  361 TKKADENGEG DAPKKIPKPA DKMETIFSLI DKKENTFNDV WLAIFTEILQ LSSVILNVAN 420
  421 YQMALTTVAE IMQMYGNAKN LRNLRLCLAH LLTKEQELLH SKSIREDFLG ELWSQMANQL 480
  481 ISETTTNSEE IKEKQLVLQM LIRHNKLNQK LSSTLLNNII SNEMLKRNEC LATIREIFIH 540
  541 ADKCGQDKAS ADLEPIIAWA YGSADRFIAA QMIHNIDSID AQLQADTFAI SIINFLDVQQ 600
  601 LRQISQSEHI VPSTERNLLA YKYNEQLICF DKDYATPFES ITHIQSETKN CLIQSNYDCL 660
  661 MRGLNFEIAK ENKPAAIIKN LNSLLKLICT MERLLHYKVF DADTYTGCPL IKRIGLYLSH 720
  721 IEFQLKANGA EILDKSDLPE ILRLEIYVLD VFRTNLVLLD YLERQPIEML VEFVGAALKL 780
  781 HSMQRERSVD ADHGTITRLC LNILAGLCAY NSHRDEAFEH IVKVTMRWHP QDVLIVTKML 840
  841 CSCQTISEAS SSWLVSKLKT LFQQHHQDAE LMDKVVQHMP TIFYFVRHKE NHLDDMLMAL 900
  901 NSLLRIAIKK SYTSNLTAKI VRCVGLIAQR CPDIYLLENF AVICKSTAKF ITMPTLEVRF 960
  961 ATLFTFTILL ESNCVTSDAI GHSRTHWDFC QELYESIEFK KLTYNNEDAI QNSNALIVQM1020
 1021 LIAIFLRSSF HQEIALKELL HHCALRRLTE REFISLQSMS SCHRQTVRDL IRPFAAILLH1080
 1081 HWSSKRWPIS KFPYFLCYST KSEFRKTHAS EIMAYTFLYG KTEDIERCSK SISEELALPI1140
 1141 LASFLLIKNS SCSESEGQNF KEHLQLLSEN LSYSQLNATD VDLDLDILCY VISMLHDPQE1200
 1201 MMRLFGSLAI CNRTASWYSL SGESLFKCLN FHIDPEMRPS MDSRIQSMTT LQTKHSRVLV1260
 1261 DIFGRLKTNC YSASFSSQAL HDFFLYCEVA DAVYDAARKN ETIVTQCSFF VRDIWFFVVR1320
 1321 LLIHTKFIRV QMAALTFLEL LLNKHNFRLD DYQNHFGDIA KLLSNFQLCC EAKEVREKTM1380
 1381 SIVMYILESK KGHINLNSFL EETTDCEFLK PLREDCKSSQ PNIDRADVAN YLRSFLLSPT1440
 1441 PERLRDLRTY IAEHKDKVQE HEKLLFGVIN KLIQMTRDAH NKTTSIDSLK CLAQIGPLKI1500
 1501 STVSYYFQTD FEAFEKSNGE PMEAFLGVVC HSLDTSLFQF DPKTHEGLVS VAIQVVNSKP1560
 1561 GSNIMERYKN LRIFADKSTA STFLHSNKQI RRIDWLSILK ATKSLSYEPW MCAFVSKVFQ1620
 1621 MCGWLGFDKL AATSFAFAKT CLLPFIKLLL ENSLEHVESL SQMLDYFFEG FTSSTAPNSQ1680
 1681 EIFRNKRAIK KFLHICEYIR IFNNWTIPIN LSNVVMASNH CQAYFLSIMY LELWACSESP1740
 1741 KSKADFLDNE CFQDGAKKAY ESIGCLDAIP GFVNPMRSRL DFLGHGSNLS TILLESDHLD1800
 1801 RASGQLCIDI MKGNGLWSFA KLQQHQNIEP DYEIFWRLGQ WDSLTDPKHQ QNQTVVRTSL1860
 1861 DLEQEFKRHH FVALRSIGQR EEENSLSAIE QAYSCVRDIL MEISVECLQS VYKYLTWLCS1920
 1921 LQQAEDFCQI QFGTQLDPAS TTKIFRKWQT ELELKYGNFS CKEYVIAHQI ALLKLAGTRA1980
 1981 SRRMSEFYQK DPISTYLMKG IEECKSAGKL NLAAKYTATL RELPNIRESI KISVLLEDAE2040
 2041 INLKMGNQQI AKAILDYVTN NNEFVYCVQR VPALRMQGEF LLDCNAETLS WVQSHKFNNS2100
 2101 LKLIDDFVQH RQTLSEKYRD IFDWHQLDAY ASKQRTAAYA TIAKYADREY QQLHDYRHSQ2160
 2161 EYQTLKDIIE QNRQTAEKVT QRENQDRRVI SVQMKRYASL DEQQLNQIEE KLTEYLRLAL2220
 2221 TNYMAYCRLD SGFSSAAIYR IISLWFTNAT SKQCQECIKD EILTVPSYKF ICAANQLTAR2280
 2281 LNSKNTSLLK GLTDLLVQCG KDHPYHTFYQ LYPLVFAHLD GENSNTERSG IARKIIAMIC2340
 2341 EKNGTAGECS KQLESLLPAL ITFANEGKTN DNRPVSDSVR NKQFDKVRRW RNLNAVHCPT2400
 2401 LELPVMPSKE YSIISVVKWT NETTQCGGLN APVKIMCVCS DGKIRAQLVK GKDDLRQDAV2460
 2461 MQQVFGIVNE LLNQDSEFIE RKLKLRTYKV TPLSMRSGIL EWCTNSVPVG HYLVVEGKGG2520
 2521 AHARYRPNDW NNNKCRKLSS DHLKSPKETR YAIYKKICEN IKPVFHYFLL EKFPIPGVWF2580
 2581 ERRLAYTNSV ATTSMVGYVL GLGDRHTQNI LVDQQTAEVI HIDFGIAFEQ GKIQTTPETV2640
 2641 PFRLTRDFVA PMGICGTKGV FAKSCEATMH ILRRYKSVFT TILEVLLYDP LFIWGVLKKK2700
 2701 QSPQQSGEES VNLVAQRALL LVQNKLDGRE AGTMGDSNVE AQVERLINEA TLPSNLCMLF2760
 2761 PGWDPHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: tefu-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: