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Protein Overview: BIG3_MOUSE

General Information:
Name(s) found: BIG3_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|85701756|ref|NP_001028430.1| hypothetical protein LOC215821 [Mus musculus] [NCBI NR]
  • gi|74188653|dbj|BAE28069.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|123784601|sp|Q3UGY8.1|BIG3_MOUSE RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 3 [NCBI NR]
  • Brefeldin A-inhibited guanine nucleotide-exchange protein 3 OS=Mus musculus GN=Arfgef3 PE=1 SV=1 [Swiss-Prot]
  • Tax_Id=10090 CDNA, RIKEN full-length enriched library, clone:M5C1106N20 product:BIG3 homolog [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • PREDICTED: hypothetical protein LOC215821 isoform 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • PREDICTED: similar to CG5937-PA isoform 3 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • hypothetical protein LOC215821 [Mus musculus] [NCBI-RefSeq_mouse_na_03-19-2007_reversed.fasta]
  • Brefeldin A-inhibited guanine nucleotide-exchange protein 3 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=D10Bwg1379e Brefeldin A-inhibited guanine nucleotide-exchange protein 3 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=D10Bwg1379e CDNA, RIKEN full-length enriched library, clone:M5C1106N20 product:BIG3 homolog [zeeyong.fasta]
  • Tax_Id=10090 Gene_Symbol=D10Bwg1379e Brefeldin A-inhibited guanine nucleotide-exchange protein 3 ENSMUSG00000019852 IPI00116462 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • brefeldin A-inhibited guanine nucleotide-exchange protein 3 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00116462.8|SWISS-PROT:Q3UGY8|ENSEMBL:ENSMUSP00000019999|REFSEQ:NP_001028430 Tax_Id=10090 Gene_Symbol=D10Bwg1379e Brefeldin A-inhibited guanine nucleotide-exchange protein 3 [ipi.MOUSE.fasta.20090209]
  • Brefeldin A-inhibited guanine nucleotide-exchange protein 3 OS=Mus musculus GN=Arfgef3 [011711_HMR.fasta]
  • sp|Q3UGY8|BIG3_MOUSE Brefeldin A-inhibited guanine nucleotide-exchange protein 3 OS=Mus musculus GN=Arfgef3 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 2170 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    cellular_component [ND]
    intracellular [IEA]
    Biological Process: biological_process [ND]
    regulation of ARF protein signal transduction [IEA]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEA]
    guanyl-nucleotide exchange factor activity [IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEILRKLQR DASGSKYKAI KESCTWALET LGGLDTVVKI PPHLLREKCL LPLQLALESK  60
   61 NVKLAQHALA GMQKLLSEER FVSMETDSDE KQLLNQILNA VKVTPSLNED LQVEVMKVLL 120
  121 CITYTPTFDM NGSAVLKIAE VCIETYTCSC HQRSINTAVR ATLSQMLGDL TLQLRQRQEN 180
  181 TIIENPDAPQ EFRSQGLTVE ALCDDVISVL AVLCEKLQAS INDSQQLQLL YLECILSVLS 240
  241 SSSSSMHLHR GFTDLIWKSL CPALVVILGN PIHDKTITSA HSTSTSTSME SDSASLGVSD 300
  301 HGRGSGCSCT APTLSGPVAR TIYYLAAELV RLVGSVDSMK PVLQSLYHRV LLYPPPQHRV 360
  361 EAIKIMKEIL GSPQRLYDLA GPSSIESEPR KRSISKRKSH LDLLKLIMDG MTEACIKGGI 420
  421 EACYAAVSCV CTLLGALDEL SQGKGLNDTQ VQQLLLRLEE LRDGAESSRD SMEINEADFR 480
  481 WQRRVLSSEH TPWESGNERS PDISISVTTD TGQTTLEGEL GQTTPEDHKN GLKSPAIQEG 540
  541 KGTMGKVSEP EAIDQPDVVQ RSHTVPYPDI TNFLSVDCRT RSYGSRYSES NFSVDDQDLS 600
  601 RTEFDSCDQY SMAAEKDSGR SDVSDIGSDN CSLADEEQTP RDYIGHRSLR TAALSLKLLK 660
  661 NQEADQHSAR LFIQSLEGLL PRLLALSSVE EVDSALQNFA STFCSGMMHS PGFDGGSSLS 720
  721 FQMLMNADSL YTAAHCALLL NLKLSHGDYY RKRPTVAPGM MKEFMKQVQT SGVLMVFSQA 780
  781 WLEELYHQVL DRNMLGEAGY WGSPEDNSLP LITMLTDIDG LESSAIGGQL MASASVESPF 840
  841 TQSRRLDDST VAGVAFARYI LVGCWKNLID TLSTPLTGRM AGSSKGLAFI LGAEGIKEQN 900
  901 QKERDAICMS LDGLRKAARL SCALGVAANC ASALAQMAAA SCVQEEKEER QSQEPSDALA 960
  961 QVKLKVEQKL EQMGKVQGVW LHTAHVLCMD AILSVGLEMG SHNPDCWPHV FRVCEYVGTL1020
 1021 EHTHFSDGIS QPPLTIHQPQ KTSGSSGLLG EIEFKSSSQE QSLEQGPSLN TAPVVQPHSI1080
 1081 QELVRECSRG RTSDFRGGSL SGNSAAKVVL SLSTQADRLF DDATDKLNLT ALGGFLYQLK1140
 1141 KASQSQLFHS VTDTVDYSLT MPGEVKSTQD QKSALHLFRL GDAMLRIVRS KARPLLHVMR1200
 1201 CWSLVAPHLV EAACHKERHV SQKAVSFIHD ILTEVLTDWS EPPHFHFNEA LFRPFERIMQ1260
 1261 LELCDEDVQD QVVTSIGELV EVCSAQIQSG WRPLFSALET VRSGNKSEVK EYLVGDYSMG1320
 1321 KGQAPVFDVF EAFLNTDNIQ VFANAATSYI MCLMKFVKGL GEVDCKEIGD CVPGAGATST1380
 1381 DLCLPALDYL RRCSQLLAKI YKMPLKPIFL SGRLASLPRR LQEQSASSED GIESVLSDFD1440
 1441 DDTGLIEVWI ILLEQLTAAV SNCPRQHQPP TLDLLFELLR DVTKTPGPGF GIYAVVHLLL1500
 1501 PVMSLWLLRS HKDHSYWDVA SANFKHAIGL SCELVVEHIQ SFLHSDIRYE SMINTMLKDL1560
 1561 FELLVVCVAK PTETISRVGC SCIRYVLVTA GPVFTEEMWR LACCALQDAF SATLKPVKDL1620
 1621 LGCFHGGTEG FSGEGCQVRV AAPSSSPSAE AEYWRIRAMA QQVFMLDTQC SPKTPNNFDH1680
 1681 AQSCQLIIEL PHDEKPNGHA KKSVSFREIV VSLLSHQVLL QNLYDILLEE FVKGPSPGEE1740
 1741 KTVQVPDTKL AGFLRYISMQ NLAVIFDLLL DSYRTAREFD TSPGLKCLLK KVSGIGGAAN1800
 1801 LYRQSAMSFN IYFHALVCAV LTNQETITAE QVKKVLFEEE ERSSDSSQQC SSEDEDIFEE1860
 1861 TAQVSPPRGK EKRQWRARLP SLSVQPVSNA DWVWLVKRLH KLCMELCNHY IQMHLDLESS1920
 1921 LEEPLTFKSD PFFILPSFQS ESSTPSTGGF SGKNTPSEDD RREHLSEPQS LRVGSGDMLM1980
 1981 LPPSPKTEKK DPGRKKEWWE SAGNKICTMA ADKTISKLMT EYKKRRQPHN LPPFPKEVKV2040
 2041 DKKGEPLGPR GPDSPLLQRP QHLIDQGQMR HSFSAGPELL RQEKRPRSGS TGSSLSVSVR2100
 2101 DAEAQIQAWT NMVLTVLNQI QILPDQTFTA LQPAVFPCIS QLTCHVTDIR VRQAVREWLG2160
 2161 RVGRVYDIIT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle