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Protein Overview: gi|74998501, gi|...

General Information:
Name(s) found: gi|74998501 [NCBI NR]
gi|62473829 [NCBI NR]
gi|61677916 [NCBI NR]
Description(s) found:
Found 9 descriptions.
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  • gi|74998501|sp|Q59E36.1|RCOR_DROME RecName: Full=REST corepressor; AltName: Full=CoREST [NCBI NR]
  • gi|62473829|ref|NP_001014752.1| CoRest, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|61677916|gb|AAX52507.1| CoRest, isoform F [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 657 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    Biological Process: negative regulation of transcription, DNA-dependent [IDA][ISS]
    Molecular Function: DNA binding [IEA]
    protein binding [IPI]
    transcription corepressor activity [IDA]
    chromatin binding [IDA]
    transcription repressor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLAERNTTD VVRNGRRSRG PSPNTHTTGG VTNSASLVGS GNNSGHSGNA NANEKTTTAV  60
   61 PGAGTPESSD DDNSTKRNGK SKAKQSEYEE KIRVGRDYQA VCPPLVPEAE RRPEQMNERA 120
  121 LLVWSPTKEI PDLKLEEYIS VAKEKYGYNG EQALGMLFWH KHDLERAVMD LANFTPFPDE 180
  181 WTIEDKVLFE QAFQFHGKSF HRIRQMLPDK SIASLVKYYY SWKKTRHRSS AMDRQEKAIK 240
  241 AVVKDGSENG SEVGSNEESD NDDKSKPLQT ADANTAIGRR TGNRRPISGP EGNRKPPKGM 300
  301 YINHDDLTAL ASCGNPSLYL AERERKLTAL MAEKNRQVME QLDKECETIN VDDVLSKPAA 360
  361 ANTESAQPRI SARWLPDEIQ VALLAIREYG KNFPTIAKVV ATKTEAHVRT FYLNNRRRYN 420
  421 LDQIVKEYEA GKSEESGAEE QTEPAVDAAA AGAATASAPS AADSTSAASA TADRKQSTEN 480
  481 SNNGVETMQE SLPKKEDPKK PELAAAVLKI GVAEAADAVA TVASSTASGV IGAATSASKP 540
  541 STSATITIID ESDTATNSSS DVVTTGLATS TGSSALSSTT SAPASKTQTS SEELSAQKSN 600
  601 PASGIAAIGA ATGGGQTANS SGSKRDSSVL PVAEQPPAKK IALSTGGGSS VAEFLAN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] deduced N/A No confident structure predictions are available.
    2 View Details [79..145] Pfam 19.69897 No description for PF01448.15 was found. No confident structure predictions are available.
    3 View Details [146..234] PSI-BLAST 21.30103 Solution Structure of the SMRT Deacetylase Activation Domain
    4 View Details [235..533] FFAS03 3.18 No description for 2iw5B was found.
    5 View Details [534..657] MSA 2.191997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle