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Protein Overview: FBpp0300193, RSG7-PA

General Information:
Name(s) found: FBpp0300193 [FlyBase]
RSG7-PA / FBpp0074124 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • type=protein; loc=X:complement(16735132..16735459,16735591..16735716,16735790..16735903,16735970..16736256,16736366..16736549,16736614..16736861,16737184..16737840); ID=FBpp0300193; name=RSG7-PB; parent=FBgn0024941,FBtr0307538; dbxref=REFSEQ:NP_001245722,GB_protein:AFH07435,FlyBase:FBpp0300193,FlyBase_Annotation_IDs:CG9108-PB; MD5=759c45e14becdc00a6b6c27cca1f732e; length=647; release=r5.56; species=Dmel; [FlyBase]
  • The gene Regulator of G-protein signalling 7 is referred to in FlyBase by the symbol Dmel\RSG7 (CG9108, FBgn0024941). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16734925..16738399. It has the cytological map location 15B1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: signal transducer activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of G-protein coupled receptor protein signaling pathway. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 647 amino acids

    Gene Ontology:
    Cellular Component: heterotrimeric G-protein complex [IEA]
    Biological Process: intracellular signaling pathway [IEA]
    regulation of G-protein coupled receptor protein signaling pathway [ISS]
    Molecular Function: signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTMNSEADK TQATNASSTA APAKTDCTSS NSSDPLAVAI PEPQSATAVV GGGAGGAAPG  60
   61 TATPSPTPLA NGSNNGTGSS VSPAATGTGA VATAASAPAA AGTTSASPPA SNPTTASTST 120
  121 ASVVGAKTAA ATTTSSSSAT SSSTAAAGSK QSGSSGGLLT VSGNHHHHHH AHPQQSAAGQ 180
  181 SAAQPPQPPT ATALAVPSAS HHQRGGKNED APNILVYKKM EAIIEKMQAE STGVAVRTVK 240
  241 AFMSKVPSVF TGADLVAWIL KNFDVEDVTE ALHFAHLLSS HGYIFPIDDH ALTVKNDGTF 300
  301 YRFQTPYFWP SNCWEPENTD YAVYLCKRTM QNKTRLELAD YEAENLAKLQ KMFSRKWEFI 360
  361 FMQAESQSKV AKKRDKLERK VLDSQERAFW DVHRPMPGCV NTTEIDIKKA YRRGGSSHGT 420
  421 GSAGASLAKN PVEQLTRIIA LRKQKLERRT IKVSKAAEAL VAYYDQYNEF DYFITSPELP 480
  481 NPWQTDSTEM WDTEKNSKEV PVRRVKRWAF SLRELLNDAI GREQFTKFLE KEYSGENLKF 540
  541 WESVQEMKAL PQSEIKEAIQ KIWQEFLAPE APCPVNVDSK SVELAREAVN SPSGPNRWCF 600
  601 DVAASHVYHL MKSDSYSRYL RSDMYKDYLN CSRKKIKSIP NLFGVKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] MSA 10.202996 View MSA. No confident structure predictions are available.
    2 View Details [212..300] Pfam 32.113509 No description for PF00610.12 was found. No confident structure predictions are available.
    3 View Details [301..397] deduced N/A No confident structure predictions are available.
    4 View Details [398..484] FFAS03 1.53 The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer
    5 View Details [485..647] PSI-BLAST 56.154902 Structure of the regulator of G-protein signaling domain of RGS6

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.90500749049821 bayes_pls_golite062009
  • signal transducer activity
    		•  1.70315911322844 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.70315911322844 bayes_pls_golite062009
  • GTPase activity
    		•  0.944482131496004 bayes_pls_golite062009
  • protein binding
    		•  0.40736300061233 bayes_pls_golite062009
  • receptor binding
    		•  0.363468238376214 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle